Difference between revisions of "YGL169W"

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'''Description of YGL169W:''' Protein required for N6-threonylcarbamoyl adenosine (t6A) modification at position 37 in the anticodon loop of ANN-decoding tRNAs; null mutant is extremely slow-growing and respiratory growth deficient; member of conserved YrdC/Sua5 family<ref name='S000054670'>Na JG, et al. (1992) Isolation and characterization of SUA5, a novel gene required for normal growth in Saccharomyces cerevisiae. Genetics 131(4):791-801 {{SGDpaper|S000054670}} PMID 1325384</ref><ref name='S000054232'>Hampsey M, et al. (1991) Extragenic suppressors of a translation initiation defect in the cyc1 gene of Saccharomyces cerevisiae. Biochimie 73(12):1445-55 {{SGDpaper|S000054232}} PMID 1666843</ref><ref name='S000129651'>El Yacoubi B, et al. (2009) The universal YrdC/Sua5 family is required for the formation of threonylcarbamoyladenosine in tRNA. Nucleic Acids Res
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'''Description of YGL169W:''' Single-stranded telomeric DNA-binding protein, required for normal telomere length; null mutant lacks N6-threonylcarbamoyl adenosine (t6A) modification in the anticodon loop of ANN-decoding tRNA; member of conserved YrdC/Sua5 family<ref name='S000054670'>Na JG, et al. (1992) Isolation and characterization of SUA5, a novel gene required for normal growth in Saccharomyces cerevisiae. Genetics 131(4):791-801 {{SGDpaper|S000054670}} PMID 1325384</ref><ref name='S000054232'>Hampsey M, et al. (1991) Extragenic suppressors of a translation initiation defect in the cyc1 gene of Saccharomyces cerevisiae. Biochimie 73(12):1445-55 {{SGDpaper|S000054232}} PMID 1666843</ref><ref name='S000129651'>El Yacoubi B, et al. (2009) The universal YrdC/Sua5 family is required for the formation of threonylcarbamoyladenosine in tRNA. Nucleic Acids Res {{SGDpaper|S000129651}} PMID 19287007</ref><ref name='S000129954'>Meng FL, et al. (2009) Sua5p a single-stranded telomeric DNA-binding protein facilitates telomere replication. EMBO J
  {{SGDpaper|S000129651}} PMID 19287007</ref>
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  {{SGDpaper|S000129954}} PMID 19369944</ref>
 
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Revision as of 14:05, 23 April 2009

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Systematic name YGL169W
Gene name SUA5
Aliases
Feature type ORF, Verified
Coordinates Chr VII:186065..187345
Primary SGDID S000003137


Description of YGL169W: Single-stranded telomeric DNA-binding protein, required for normal telomere length; null mutant lacks N6-threonylcarbamoyl adenosine (t6A) modification in the anticodon loop of ANN-decoding tRNA; member of conserved YrdC/Sua5 family[1][2][3][4]




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References

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  1. Na JG, et al. (1992) Isolation and characterization of SUA5, a novel gene required for normal growth in Saccharomyces cerevisiae. Genetics 131(4):791-801 SGD PMID 1325384
  2. Hampsey M, et al. (1991) Extragenic suppressors of a translation initiation defect in the cyc1 gene of Saccharomyces cerevisiae. Biochimie 73(12):1445-55 SGD PMID 1666843
  3. El Yacoubi B, et al. (2009) The universal YrdC/Sua5 family is required for the formation of threonylcarbamoyladenosine in tRNA. Nucleic Acids Res SGD PMID 19287007
  4. Meng FL, et al. (2009) Sua5p a single-stranded telomeric DNA-binding protein facilitates telomere replication. EMBO J SGD PMID 19369944

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