YGL169W

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Systematic name YGL169W
Gene name SUA5
Aliases
Feature type ORF, Verified
Coordinates Chr VII:186059..187339
Primary SGDID S000003137


Description of YGL169W: Single-stranded telomeric DNA-binding protein, required for normal telomere length; null mutant lacks N6-threonylcarbamoyl adenosine (t6A) modification in the anticodon loop of ANN-decoding tRNA; member of conserved YrdC/Sua5 family[1][2][3][4]




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References

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  1. El Yacoubi B, et al. (2009) The universal YrdC/Sua5 family is required for the formation of threonylcarbamoyladenosine in tRNA. Nucleic Acids Res 37(9):2894-909 SGD PMID 19287007
  2. Hampsey M, et al. (1991) Extragenic suppressors of a translation initiation defect in the cyc1 gene of Saccharomyces cerevisiae. Biochimie 73(12):1445-55 SGD PMID 1666843
  3. Meng FL, et al. (2009) Sua5p a single-stranded telomeric DNA-binding protein facilitates telomere replication. EMBO J 28(10):1466-78 SGD PMID 19369944
  4. Na JG, et al. (1992) Isolation and characterization of SUA5, a novel gene required for normal growth in Saccharomyces cerevisiae. Genetics 131(4):791-801 SGD PMID 1325384

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