Difference between revisions of "YGL145W"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003113 YGL145W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''TIP20 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''TIP20 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr VII: | + | |nowrap| Chr VII:230243..232348 |
|- | |- | ||
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000003113 | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000003113 | ||
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| − | '''Description of YGL145W:''' Peripheral membrane protein required for fusion of COPI vesicles with the ER | + | '''Description of YGL145W:''' Peripheral membrane protein required for fusion of COPI vesicles with the ER; prohibits back-fusion of COPII vesicles with the ER; forms a tethering complex with Sec39p and Dsl1p that interacts with ER SNAREs Sec20p and Use1p<ref name='S000076158'>Kamena F and Spang A (2004) Tip20p prohibits back-fusion of COPII vesicles with the endoplasmic reticulum. Science 304(5668):286-9 {{SGDpaper|S000076158}} PMID 15073376</ref><ref name='S000131405'>Tripathi A, et al. (2009) Structural characterization of Tip20p and Dsl1p, subunits of the Dsl1p vesicle tethering complex. Nat Struct Mol Biol 16(2):114-23 |
| − | {{SGDpaper| | + | {{SGDpaper|S000131405}} PMID 19151722</ref> |
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Latest revision as of 07:45, 23 January 2012
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| Systematic name | YGL145W |
| Gene name | TIP20 |
| Aliases | TIP1 |
| Feature type | ORF, Verified |
| Coordinates | Chr VII:230243..232348 |
| Primary SGDID | S000003113 |
Description of YGL145W: Peripheral membrane protein required for fusion of COPI vesicles with the ER; prohibits back-fusion of COPII vesicles with the ER; forms a tethering complex with Sec39p and Dsl1p that interacts with ER SNAREs Sec20p and Use1p[1][2]
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References
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- ↑ Kamena F and Spang A (2004) Tip20p prohibits back-fusion of COPII vesicles with the endoplasmic reticulum. Science 304(5668):286-9 SGD PMID 15073376
- ↑ Tripathi A, et al. (2009) Structural characterization of Tip20p and Dsl1p, subunits of the Dsl1p vesicle tethering complex. Nat Struct Mol Biol 16(2):114-23 SGD PMID 19151722
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