Difference between revisions of "YGL097W"
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| − | '''Description of YGL097W:''' Nucleotide exchange factor for Gsp1p, localizes to the nucleus, required for nucleocytoplasmic trafficking of macromolecules; suppressor of the pheromone response pathway; potentially phosphorylated by Cdc28p<ref name=' | + | '''Description of YGL097W:''' Nucleotide exchange factor for Gsp1p, localizes to the nucleus, required for nucleocytoplasmic trafficking of macromolecules; suppressor of the pheromone response pathway; potentially phosphorylated by Cdc28p<ref name='S000074306'>Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 {{SGDpaper|S000074306}} PMID 14574415</ref><ref name='S000066018'>Clement M, et al. (2001) Overexpression of Bud5p can suppress mutations in the Gsp1p guanine nucleotide exchange factor Prp20p in Saccharomyces cerevisiae. Mol Genet Genomics 266(1):20-7 {{SGDpaper|S000066018}} PMID 11589573</ref><ref name='S000065839'>Akhtar N, et al. (2001) Functional analysis of the yeast Ran exchange factor Prp20p: in vivo evidence for the RanGTP gradient model. Mol Genet Genomics 265(5):851-64 {{SGDpaper|S000065839}} PMID 11523802</ref><ref name='S000049056'>Clark KL and Sprague GF Jr (1989) Yeast pheromone response pathway: characterization of a suppressor that restores mating to receptorless mutants. Mol Cell Biol 9(6):2682-94 |
| − | {{SGDpaper| | + | {{SGDpaper|S000049056}} PMID 2548085</ref> |
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Revision as of 14:05, 16 January 2009
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| Systematic name | YGL097W |
| Gene name | SRM1 |
| Aliases | MTR1, PRP20 |
| Feature type | ORF, Verified |
| Coordinates | Chr VII:321785..323233 |
| Primary SGDID | S000003065 |
Description of YGL097W: Nucleotide exchange factor for Gsp1p, localizes to the nucleus, required for nucleocytoplasmic trafficking of macromolecules; suppressor of the pheromone response pathway; potentially phosphorylated by Cdc28p[1][2][3][4]
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Protein Details
Protein Modification
Modification(s): Phosphorylation
Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [1] [5]
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References
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- ↑ 1.0 1.1 Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
- ↑ Clement M, et al. (2001) Overexpression of Bud5p can suppress mutations in the Gsp1p guanine nucleotide exchange factor Prp20p in Saccharomyces cerevisiae. Mol Genet Genomics 266(1):20-7 SGD PMID 11589573
- ↑ Akhtar N, et al. (2001) Functional analysis of the yeast Ran exchange factor Prp20p: in vivo evidence for the RanGTP gradient model. Mol Genet Genomics 265(5):851-64 SGD PMID 11523802
- ↑ Clark KL and Sprague GF Jr (1989) Yeast pheromone response pathway: characterization of a suppressor that restores mating to receptorless mutants. Mol Cell Biol 9(6):2682-94 SGD PMID 2548085
- ↑ submitted by Jeff Ubersax on 2004-01-27
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