YGL097W
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| Systematic name | YGL097W |
| Gene name | SRM1 |
| Aliases | MTR1, PRP20 |
| Feature type | ORF, Verified |
| Coordinates | Chr VII:321782..323230 |
| Primary SGDID | S000003065 |
Description of YGL097W: Nucleotide exchange factor for Gsp1p, localizes to the nucleus, required for nucleocytoplasmic trafficking of macromolecules; suppressor of the pheromone response pathway; potentially phosphorylated by Cdc28p[1][2][3][4]
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Protein Details
Protein Modification
Modification(s): Phosphorylation
Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [4] [5]
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References
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- Jump up ↑ Akhtar N, et al. (2001) Functional analysis of the yeast Ran exchange factor Prp20p: in vivo evidence for the RanGTP gradient model. Mol Genet Genomics 265(5):851-64 SGD PMID 11523802
- Jump up ↑ Clark KL and Sprague GF Jr (1989) Yeast pheromone response pathway: characterization of a suppressor that restores mating to receptorless mutants. Mol Cell Biol 9(6):2682-94 SGD PMID 2548085
- Jump up ↑ Clement M, et al. (2001) Overexpression of Bud5p can suppress mutations in the Gsp1p guanine nucleotide exchange factor Prp20p in Saccharomyces cerevisiae. Mol Genet Genomics 266(1):20-7 SGD PMID 11589573
- ↑ Jump up to: 4.0 4.1 Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64
SGD PMID 14574415 Cite error: Invalid
<ref>tag; name "S000074306" defined multiple times with different content - Jump up ↑ submitted by Jeff Ubersax on 2004-01-27
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