YGL077C

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Systematic name YGL077C
Gene name HNM1
Aliases
Feature type ORF, Verified
Coordinates Chr VII:363919..362228
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Description of YGL077C: Choline transporter (permease) that also controls the uptake of nitrogen mustard; expression is co-regulated with phospholipid biosynthetic genes and negatively regulated by choline and myo-inositol[1][2][3]



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References

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  1. Nikawa J, et al. (1990) Primary structure of the yeast choline transport gene and regulation of its expression. J Biol Chem 265(26):15996-6003 SGD PMID 2203793
  2. Li ZY, et al. (1991) Hyper-resistance to nitrogen mustard in Saccharomyces cerevisiae is caused by defective choline transport. Curr Genet 19(6):423-7 SGD PMID 1878995
  3. Li Z and Brendel M (1993) Co-regulation with genes of phospholipid biosynthesis of the CTR/HNM1-encoded choline/nitrogen mustard permease in Saccharomyces cerevisiae. Mol Gen Genet 241(5-6):680-4 SGD PMID 8264542

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