YGL077C
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| Systematic name | YGL077C |
| Gene name | HNM1 |
| Aliases | CTR1 |
| Feature type | ORF, Verified |
| Coordinates | Chr VII:363916..362225 |
| Primary SGDID | S000003045 |
Description of YGL077C: Choline/ethanolamine transporter; involved in the uptake of nitrogen mustard and the uptake of glycine betaine during hypersaline stress; co-regulated with phospholipid biosynthetic genes and negatively regulated by choline and myo-inositol[1][2][3][4][5]
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References
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- ↑ Kiewietdejonge A, et al. (2006) Hypersaline stress induces the turnover of phosphatidylcholine and results in the synthesis of the renal osmoprotectant glycerophosphocholine in Saccharomyces cerevisiae. FEMS Yeast Res 6(2):205-17 SGD PMID 16487344
- ↑ Li Z and Brendel M (1993) Co-regulation with genes of phospholipid biosynthesis of the CTR/HNM1-encoded choline/nitrogen mustard permease in Saccharomyces cerevisiae. Mol Gen Genet 241(5-6):680-4 SGD PMID 8264542
- ↑ Li ZY, et al. (1991) Hyper-resistance to nitrogen mustard in Saccharomyces cerevisiae is caused by defective choline transport. Curr Genet 19(6):423-7 SGD PMID 1878995
- ↑ Nikawa J, et al. (1986) Cloning of a gene encoding choline transport in Saccharomyces cerevisiae. J Bacteriol 166(1):328-30 SGD PMID 3514579
- ↑ Nikawa J, et al. (1990) Primary structure of the yeast choline transport gene and regulation of its expression. J Biol Chem 265(26):15996-6003 SGD PMID 2203793
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