Difference between revisions of "YGL077C"

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'''Description of YGL077C:''' Choline/ethanolamine transporter; involved in the uptake of nitrogen mustard and the uptake of glycine betaine during hypersaline stress; co-regulated with phospholipid biosynthetic genes and negatively regulated by choline and myo-inositol<ref name='S000114466'>Kiewietdejonge A, et al. (2006) Hypersaline stress induces the turnover of phosphatidylcholine and results in the synthesis of the renal osmoprotectant glycerophosphocholine in Saccharomyces cerevisiae. FEMS Yeast Res 6(2):205-17 {{SGDpaper|S000114466}} PMID 16487344</ref><ref name='S000063526'>Nikawa J, et al. (1986) Cloning of a gene encoding choline transport in Saccharomyces cerevisiae. J Bacteriol 166(1):328-30 {{SGDpaper|S000063526}} PMID 3514579</ref><ref name='S000056806'>Nikawa J, et al. (1990) Primary structure of the yeast choline transport gene and regulation of its expression. J Biol Chem 265(26):15996-6003 {{SGDpaper|S000056806}} PMID 2203793</ref><ref name='S000055153'>Li ZY, et al. (1991) Hyper-resistance to nitrogen mustard in Saccharomyces cerevisiae is caused by defective choline transport. Curr Genet 19(6):423-7 {{SGDpaper|S000055153}} PMID 1878995</ref><ref name='S000050011'>Li Z and Brendel M (1993) Co-regulation with genes of phospholipid biosynthesis of the CTR/HNM1-encoded choline/nitrogen mustard permease in Saccharomyces cerevisiae. Mol Gen Genet 241(5-6):680-4
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'''Description of YGL077C:''' Choline/ethanolamine transporter; involved in the uptake of nitrogen mustard and the uptake of glycine betaine during hypersaline stress; co-regulated with phospholipid biosynthetic genes and negatively regulated by choline and myo-inositol<ref name='S000050011'>Li Z and Brendel M (1993) Co-regulation with genes of phospholipid biosynthesis of the CTR/HNM1-encoded choline/nitrogen mustard permease in Saccharomyces cerevisiae. Mol Gen Genet 241(5-6):680-4 {{SGDpaper|S000050011}} PMID 8264542</ref><ref name='S000055153'>Li ZY, et al. (1991) Hyper-resistance to nitrogen mustard in Saccharomyces cerevisiae is caused by defective choline transport. Curr Genet 19(6):423-7 {{SGDpaper|S000055153}} PMID 1878995</ref><ref name='S000056806'>Nikawa J, et al. (1990) Primary structure of the yeast choline transport gene and regulation of its expression. J Biol Chem 265(26):15996-6003 {{SGDpaper|S000056806}} PMID 2203793</ref><ref name='S000063526'>Nikawa J, et al. (1986) Cloning of a gene encoding choline transport in Saccharomyces cerevisiae. J Bacteriol 166(1):328-30 {{SGDpaper|S000063526}} PMID 3514579</ref><ref name='S000114466'>Kiewietdejonge A, et al. (2006) Hypersaline stress induces the turnover of phosphatidylcholine and results in the synthesis of the renal osmoprotectant glycerophosphocholine in Saccharomyces cerevisiae. FEMS Yeast Res 6(2):205-17
  {{SGDpaper|S000050011}} PMID 8264542</ref>
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  {{SGDpaper|S000114466}} PMID 16487344</ref>
 
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Revision as of 13:05, 31 March 2009

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Systematic name YGL077C
Gene name HNM1
Aliases CTR1
Feature type ORF, Verified
Coordinates Chr VII:363919..362228
Primary SGDID S000003045


Description of YGL077C: Choline/ethanolamine transporter; involved in the uptake of nitrogen mustard and the uptake of glycine betaine during hypersaline stress; co-regulated with phospholipid biosynthetic genes and negatively regulated by choline and myo-inositol[1][2][3][4][5]




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References

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  1. Li Z and Brendel M (1993) Co-regulation with genes of phospholipid biosynthesis of the CTR/HNM1-encoded choline/nitrogen mustard permease in Saccharomyces cerevisiae. Mol Gen Genet 241(5-6):680-4 SGD PMID 8264542
  2. Li ZY, et al. (1991) Hyper-resistance to nitrogen mustard in Saccharomyces cerevisiae is caused by defective choline transport. Curr Genet 19(6):423-7 SGD PMID 1878995
  3. Nikawa J, et al. (1990) Primary structure of the yeast choline transport gene and regulation of its expression. J Biol Chem 265(26):15996-6003 SGD PMID 2203793
  4. Nikawa J, et al. (1986) Cloning of a gene encoding choline transport in Saccharomyces cerevisiae. J Bacteriol 166(1):328-30 SGD PMID 3514579
  5. Kiewietdejonge A, et al. (2006) Hypersaline stress induces the turnover of phosphatidylcholine and results in the synthesis of the renal osmoprotectant glycerophosphocholine in Saccharomyces cerevisiae. FEMS Yeast Res 6(2):205-17 SGD PMID 16487344

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