Difference between revisions of "YGL077C"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003045 YGL077C] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''HNM1 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''HNM1 '' | ||
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases''' ||'' '' | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases''' ||''CTR1'' |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type''' || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]] | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type''' || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]] | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr VII: | + | |nowrap| Chr VII:363916..362225 |
| + | |- | ||
| + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000003045 | ||
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<br> | <br> | ||
| − | '''Description of | + | '''Description of YGL077C:''' Choline/ethanolamine transporter; involved in the uptake of nitrogen mustard and the uptake of glycine betaine during hypersaline stress; co-regulated with phospholipid biosynthetic genes and negatively regulated by choline and myo-inositol<ref name='S000114466'>Kiewietdejonge A, et al. (2006) Hypersaline stress induces the turnover of phosphatidylcholine and results in the synthesis of the renal osmoprotectant glycerophosphocholine in Saccharomyces cerevisiae. FEMS Yeast Res 6(2):205-17 {{SGDpaper|S000114466}} PMID 16487344</ref><ref name='S000050011'>Li Z and Brendel M (1993) Co-regulation with genes of phospholipid biosynthesis of the CTR/HNM1-encoded choline/nitrogen mustard permease in Saccharomyces cerevisiae. Mol Gen Genet 241(5-6):680-4 {{SGDpaper|S000050011}} PMID 8264542</ref><ref name='S000055153'>Li ZY, et al. (1991) Hyper-resistance to nitrogen mustard in Saccharomyces cerevisiae is caused by defective choline transport. Curr Genet 19(6):423-7 {{SGDpaper|S000055153}} PMID 1878995</ref><ref name='S000063526'>Nikawa J, et al. (1986) Cloning of a gene encoding choline transport in Saccharomyces cerevisiae. J Bacteriol 166(1):328-30 {{SGDpaper|S000063526}} PMID 3514579</ref><ref name='S000056806'>Nikawa J, et al. (1990) Primary structure of the yeast choline transport gene and regulation of its expression. J Biol Chem 265(26):15996-6003 |
| − | {{SGDpaper| | + | {{SGDpaper|S000056806}} PMID 2203793</ref> |
<br> | <br> | ||
<br> | <br> | ||
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==Community Commentary== | ==Community Commentary== | ||
{{CommentaryHelp}} | {{CommentaryHelp}} | ||
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| + | <!-- PLEASE ADD Community Commentary ABOVE THIS MESSAGE. See below for an example of community annotation --> | ||
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| + | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
| + | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
| + | J Biol Chem 278(5):3265-74</ref> | ||
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Latest revision as of 06:45, 23 January 2012
Share your knowledge...Edit this entry! <protect>
| Systematic name | YGL077C |
| Gene name | HNM1 |
| Aliases | CTR1 |
| Feature type | ORF, Verified |
| Coordinates | Chr VII:363916..362225 |
| Primary SGDID | S000003045 |
Description of YGL077C: Choline/ethanolamine transporter; involved in the uptake of nitrogen mustard and the uptake of glycine betaine during hypersaline stress; co-regulated with phospholipid biosynthetic genes and negatively regulated by choline and myo-inositol[1][2][3][4][5]
</protect>
Contents
Community Commentary
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References
See Help:References on how to add references
- ↑ Kiewietdejonge A, et al. (2006) Hypersaline stress induces the turnover of phosphatidylcholine and results in the synthesis of the renal osmoprotectant glycerophosphocholine in Saccharomyces cerevisiae. FEMS Yeast Res 6(2):205-17 SGD PMID 16487344
- ↑ Li Z and Brendel M (1993) Co-regulation with genes of phospholipid biosynthesis of the CTR/HNM1-encoded choline/nitrogen mustard permease in Saccharomyces cerevisiae. Mol Gen Genet 241(5-6):680-4 SGD PMID 8264542
- ↑ Li ZY, et al. (1991) Hyper-resistance to nitrogen mustard in Saccharomyces cerevisiae is caused by defective choline transport. Curr Genet 19(6):423-7 SGD PMID 1878995
- ↑ Nikawa J, et al. (1986) Cloning of a gene encoding choline transport in Saccharomyces cerevisiae. J Bacteriol 166(1):328-30 SGD PMID 3514579
- ↑ Nikawa J, et al. (1990) Primary structure of the yeast choline transport gene and regulation of its expression. J Biol Chem 265(26):15996-6003 SGD PMID 2203793
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