Difference between revisions of "YFR046C"
SGDwikiBot (talk | contribs) (Automated import of articles) |
SGDwikiBot (talk | contribs) (Automated import of articles) |
||
| Line 18: | Line 18: | ||
|} | |} | ||
<br> | <br> | ||
| − | '''Description of YFR046C:''' Kinetochore protein of | + | '''Description of YFR046C:''' Kinetochore protein with a role in chromosome segregation; homologue of human CENP-T and S. pombe Cnp20; interacts with SPC24-SPC25 subunits of the Ndc80 complex; associated with the essential kinetochore proteins Nnf1p and Spc24p; phosphorylated by both Clb5-Cdk1 and, to a lesser extent, Clb2-Cdk1.<ref name='S000150766'>Bock LJ, et al. (2012) Cnn1 inhibits the interactions between the KMN complexes of the yeast kinetochore. Nat Cell Biol 14(6):614-24 {{SGDpaper|S000150766}} PMID 22561345</ref><ref name='S000061559'>Cho RJ, et al. (1998) Parallel analysis of genetic selections using whole genome oligonucleotide arrays. Proc Natl Acad Sci U S A 95(7):3752-7 {{SGDpaper|S000061559}} PMID 9520439</ref><ref name='S000075142'>De Wulf P, et al. (2003) Hierarchical assembly of the budding yeast kinetochore from multiple subcomplexes. Genes Dev 17(23):2902-21 {{SGDpaper|S000075142}} PMID 14633972</ref><ref name='S000081002'>Loog M and Morgan DO (2005) Cyclin specificity in the phosphorylation of cyclin-dependent kinase substrates. Nature 434(7029):104-8 {{SGDpaper|S000081002}} PMID 15744308</ref><ref name='S000074306'>Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 |
{{SGDpaper|S000074306}} PMID 14574415</ref> | {{SGDpaper|S000074306}} PMID 14574415</ref> | ||
<br> | <br> | ||
Revision as of 14:05, 10 September 2012
Share your knowledge...Edit this entry! <protect>
| Systematic name | YFR046C |
| Gene name | CNN1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr VI:244159..243074 |
| Primary SGDID | S000001942 |
Description of YFR046C: Kinetochore protein with a role in chromosome segregation; homologue of human CENP-T and S. pombe Cnp20; interacts with SPC24-SPC25 subunits of the Ndc80 complex; associated with the essential kinetochore proteins Nnf1p and Spc24p; phosphorylated by both Clb5-Cdk1 and, to a lesser extent, Clb2-Cdk1.[1][2][3][4][5]
</protect>
Community Commentary
About Community Commentary. Please share your knowledge!
Protein Details
Protein Modification
Modification(s): Phosphorylation
Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [5] [6]
<protect>
References
See Help:References on how to add references
- ↑ Bock LJ, et al. (2012) Cnn1 inhibits the interactions between the KMN complexes of the yeast kinetochore. Nat Cell Biol 14(6):614-24 SGD PMID 22561345
- ↑ Cho RJ, et al. (1998) Parallel analysis of genetic selections using whole genome oligonucleotide arrays. Proc Natl Acad Sci U S A 95(7):3752-7 SGD PMID 9520439
- ↑ De Wulf P, et al. (2003) Hierarchical assembly of the budding yeast kinetochore from multiple subcomplexes. Genes Dev 17(23):2902-21 SGD PMID 14633972
- ↑ Loog M and Morgan DO (2005) Cyclin specificity in the phosphorylation of cyclin-dependent kinase substrates. Nature 434(7029):104-8 SGD PMID 15744308
- ↑ 5.0 5.1 Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64
SGD PMID 14574415 Cite error: Invalid
<ref>tag; name "S000074306" defined multiple times with different content - ↑ submitted by Jeff Ubersax on 2004-01-27
See Help:Categories on how to add the wiki page for this gene to a Category </protect>
