Difference between revisions of "YFR028C"

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'''Description of YFR028C:''' Protein phosphatase required for mitotic exit; located in the nucleolus until liberated by the FEAR and Mitotic Exit Network in anaphase, enabling it to act on key substrates to effect a decrease in CDK/B-cyclin activity and mitotic exit<ref name='S000040654'>Wan J, et al. (1992) CDC14 of Saccharomyces cerevisiae. Cloning, sequence analysis, and transcription during the cell cycle. J Biol Chem 267(16):11274-80 {{SGDpaper|S000040654}} PMID 1597462</ref><ref name='S000047585'>Visintin R, et al. (1998) The phosphatase Cdc14 triggers mitotic exit by reversal of Cdk-dependent phosphorylation. Mol Cell 2(6):709-18 {{SGDpaper|S000047585}} PMID 9885559</ref><ref name='S000051434'>Taylor GS, et al. (1997) The activity of Cdc14p, an oligomeric dual specificity protein phosphatase from Saccharomyces cerevisiae, is required for cell cycle progression. J Biol Chem 272(38):24054-63 {{SGDpaper|S000051434}} PMID 9295359</ref><ref name='S000069539'>Saunders WS (2002) The FEAR factor. Mol Cell 9(2):207-9
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'''Description of YFR028C:''' Protein phosphatase required for mitotic exit; located in the nucleolus until liberated by the FEAR and Mitotic Exit Network in anaphase, enabling it to act on key substrates to effect a decrease in CDK/B-cyclin activity and mitotic exit<ref name='S000069539'>Saunders WS (2002) The FEAR factor. Mol Cell 9(2):207-9 {{SGDpaper|S000069539}} PMID 11864593</ref><ref name='S000051434'>Taylor GS, et al. (1997) The activity of Cdc14p, an oligomeric dual specificity protein phosphatase from Saccharomyces cerevisiae, is required for cell cycle progression. J Biol Chem 272(38):24054-63 {{SGDpaper|S000051434}} PMID 9295359</ref><ref name='S000047585'>Visintin R, et al. (1998) The phosphatase Cdc14 triggers mitotic exit by reversal of Cdk-dependent phosphorylation. Mol Cell 2(6):709-18 {{SGDpaper|S000047585}} PMID 9885559</ref><ref name='S000040654'>Wan J, et al. (1992) CDC14 of Saccharomyces cerevisiae. Cloning, sequence analysis, and transcription during the cell cycle. J Biol Chem 267(16):11274-80
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  {{SGDpaper|S000040654}} PMID 1597462</ref>
 
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Revision as of 14:05, 25 February 2010

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Systematic name YFR028C
Gene name CDC14
Aliases OAF3
Feature type ORF, Verified
Coordinates Chr VI:210056..208401
Primary SGDID S000001924


Description of YFR028C: Protein phosphatase required for mitotic exit; located in the nucleolus until liberated by the FEAR and Mitotic Exit Network in anaphase, enabling it to act on key substrates to effect a decrease in CDK/B-cyclin activity and mitotic exit[1][2][3][4]




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References

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  1. Saunders WS (2002) The FEAR factor. Mol Cell 9(2):207-9 SGD PMID 11864593
  2. Taylor GS, et al. (1997) The activity of Cdc14p, an oligomeric dual specificity protein phosphatase from Saccharomyces cerevisiae, is required for cell cycle progression. J Biol Chem 272(38):24054-63 SGD PMID 9295359
  3. Visintin R, et al. (1998) The phosphatase Cdc14 triggers mitotic exit by reversal of Cdk-dependent phosphorylation. Mol Cell 2(6):709-18 SGD PMID 9885559
  4. Wan J, et al. (1992) CDC14 of Saccharomyces cerevisiae. Cloning, sequence analysis, and transcription during the cell cycle. J Biol Chem 267(16):11274-80 SGD PMID 1597462

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