Difference between revisions of "YFL007W"

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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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Revision as of 13:02, 21 February 2007

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Systematic name YFL007W
Gene name BLM10
Aliases YFL006W
Feature type ORF, Verified
Coordinates Chr VI:123474..129905


Description of YFL007W: Proteosome activator subunit; found in association with core particles, with and without the 19S regulatory particle; required for resistance to bleomycin, may be involved in protecting against oxidative damage; similar to mammalian PA200[1][2][3][4][5]




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References

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  1. Ustrell V, et al. (2002) PA200, a nuclear proteasome activator involved in DNA repair. EMBO J 21(13):3516-25 SGD PMID 12093752
  2. Schmidt M, et al. (2005) The HEAT repeat protein Blm10 regulates the yeast proteasome by capping the core particle. Nat Struct Mol Biol 12(4):294-303 SGD PMID 15778719
  3. Doherty K, et al. (2004) Expression of the expanded YFL007w ORF and assignment of the gene name BLM10. Yeast 21(12):1021-3 SGD PMID 15449308
  4. Fehlker M, et al. (2003) Blm3 is part of nascent proteasomes and is involved in a late stage of nuclear proteasome assembly. EMBO Rep 4(10):959-63 SGD PMID 12973301
  5. Febres DE, et al. (2001) The novel BLM3 gene encodes a protein that protects against lethal effects of oxidative damage. Cell Mol Biol (Noisy-le-grand) 47(7):1149-62 SGD PMID 11842813

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