YER179W

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Systematic name YER179W
Gene name DMC1
Aliases ISC2
Feature type ORF, Verified
Coordinates Chr V:548416..549512
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Description of YER179W: Meiosis-specific protein required for repair of double-strand breaks and pairing between homologous chromosomes; homolog of Rad51p and the bacterial RecA protein[1][2][3]



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References

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  1. Symington LS (2002) Role of RAD52 epistasis group genes in homologous recombination and double-strand break repair. Microbiol Mol Biol Rev 66(4):630-70, table of contents SGD PMID 12456786
  2. Bishop DK, et al. (1992) DMC1: a meiosis-specific yeast homolog of E. coli recA required for recombination, synaptonemal complex formation, and cell cycle progression. Cell 69(3):439-56 SGD PMID 1581960
  3. Schwacha A and Kleckner N (1997) Interhomolog bias during meiotic recombination: meiotic functions promote a highly differentiated interhomolog-only pathway. Cell 90(6):1123-35 SGD PMID 9323140

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