Difference between revisions of "YER179W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YER179W YER179W]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000000981 YER179W]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''DMC1 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''DMC1 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr V:548416..549512
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|nowrap| Chr V:548421..549517
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000000981
 
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'''Description of {{PAGENAME}}:''' Meiosis-specific protein required for repair of double-strand breaks and pairing between homologous chromosomes; homolog of Rad51p and the bacterial RecA protein<ref name='S000071925'>Symington LS (2002) Role of RAD52 epistasis group genes in homologous recombination and double-strand break repair. Microbiol Mol Biol Rev 66(4):630-70, table of contents {{SGDpaper|S000071925}} PMID 12456786</ref><ref name='S000047546'>Bishop DK, et al. (1992) DMC1: a meiosis-specific yeast homolog of E. coli recA required for recombination, synaptonemal complex formation, and cell cycle progression. Cell 69(3):439-56 {{SGDpaper|S000047546}} PMID 1581960</ref><ref name='S000046433'>Schwacha A and Kleckner N (1997) Interhomolog bias during meiotic recombination: meiotic functions promote a highly differentiated interhomolog-only pathway. Cell 90(6):1123-35
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'''Description of YER179W:''' Meiosis-specific protein required for repair of double-strand breaks and pairing between homologous chromosomes; homolog of Rad51p and the bacterial RecA protein; binds ssDNA and dsDNA, forms helical filaments; stimulated by Rdh54p<ref name='S000047546'>Bishop DK, et al. (1992) DMC1: a meiosis-specific yeast homolog of E. coli recA required for recombination, synaptonemal complex formation, and cell cycle progression. Cell 69(3):439-56 {{SGDpaper|S000047546}} PMID 1581960</ref><ref name='S000150037'>Nimonkar AV, et al. (2012) Saccharomyces cerevisiae Dmc1 and Rad51 preferentially function with Tid1 and Rad54, respectively, to promote DNA strand invasion during genetic recombination. J Biol Chem () {{SGDpaper|S000150037}} PMID 22761450</ref><ref name='S000046433'>Schwacha A and Kleckner N (1997) Interhomolog bias during meiotic recombination: meiotic functions promote a highly differentiated interhomolog-only pathway. Cell 90(6):1123-35 {{SGDpaper|S000046433}} PMID 9323140</ref><ref name='S000071925'>Symington LS (2002) Role of RAD52 epistasis group genes in homologous recombination and double-strand break repair. Microbiol Mol Biol Rev 66(4):630-70, table of contents
  {{SGDpaper|S000046433}} PMID 9323140</ref>
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  {{SGDpaper|S000071925}} PMID 12456786</ref>
 
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J Biol Chem 278(5):3265-74</ref>
 
J Biol Chem 278(5):3265-74</ref>
 
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Latest revision as of 14:05, 16 July 2012

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Systematic name YER179W
Gene name DMC1
Aliases ISC2
Feature type ORF, Verified
Coordinates Chr V:548421..549517
Primary SGDID S000000981


Description of YER179W: Meiosis-specific protein required for repair of double-strand breaks and pairing between homologous chromosomes; homolog of Rad51p and the bacterial RecA protein; binds ssDNA and dsDNA, forms helical filaments; stimulated by Rdh54p[1][2][3][4]




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References

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  1. Bishop DK, et al. (1992) DMC1: a meiosis-specific yeast homolog of E. coli recA required for recombination, synaptonemal complex formation, and cell cycle progression. Cell 69(3):439-56 SGD PMID 1581960
  2. Nimonkar AV, et al. (2012) Saccharomyces cerevisiae Dmc1 and Rad51 preferentially function with Tid1 and Rad54, respectively, to promote DNA strand invasion during genetic recombination. J Biol Chem () SGD PMID 22761450
  3. Schwacha A and Kleckner N (1997) Interhomolog bias during meiotic recombination: meiotic functions promote a highly differentiated interhomolog-only pathway. Cell 90(6):1123-35 SGD PMID 9323140
  4. Symington LS (2002) Role of RAD52 epistasis group genes in homologous recombination and double-strand break repair. Microbiol Mol Biol Rev 66(4):630-70, table of contents SGD PMID 12456786

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