Difference between revisions of "YER008C"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000000810 YER008C]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000000810 YER008C]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''SEC3 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''SEC3 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr V:171817..167807
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|nowrap| Chr V:171818..167808
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000000810
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000000810
 
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'''Description of YER008C:''' Non-essential subunit of the exocyst complex (Sec3p, Sec5p, Sec6p, Sec8p, Sec10p, Sec15p, Exo70p, Exo84p) which mediates targeting of post-Golgi vesicles to sites of active exocytosis; Sec3p specifically is a spatial landmark for secretion<ref name='S000039481'>Finger FP and Novick P (1998) Spatial regulation of exocytosis: lessons from yeast. J Cell Biol 142(3):609-12 {{SGDpaper|S000039481}} PMID 9700152</ref><ref name='S000041326'>Finger FP, et al. (1998) Sec3p is a spatial landmark for polarized secretion in budding yeast. Cell 92(4):559-71 {{SGDpaper|S000041326}} PMID 9491896</ref><ref name='S000047160'>TerBush DR, et al. (1996) The Exocyst is a multiprotein complex required for exocytosis in Saccharomyces cerevisiae. EMBO J 15(23):6483-94
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'''Description of YER008C:''' Subunit of the exocyst complex (Sec3p, Sec5p, Sec6p, Sec8p, Sec10p, Sec15p, Exo70p, Exo84p) which mediates targeting of post-Golgi vesicles to sites of active exocytosis; Sec3p specifically is a spatial landmark for secretion<ref name='S000039481'>Finger FP and Novick P (1998) Spatial regulation of exocytosis: lessons from yeast. J Cell Biol 142(3):609-12 {{SGDpaper|S000039481}} PMID 9700152</ref><ref name='S000041326'>Finger FP, et al. (1998) Sec3p is a spatial landmark for polarized secretion in budding yeast. Cell 92(4):559-71 {{SGDpaper|S000041326}} PMID 9491896</ref><ref name='S000049442'>TerBush DR and Novick P (1995) Sec6, Sec8, and Sec15 are components of a multisubunit complex which localizes to small bud tips in Saccharomyces cerevisiae. J Cell Biol 130(2):299-312 {{SGDpaper|S000049442}} PMID 7615633</ref><ref name='S000047160'>TerBush DR, et al. (1996) The Exocyst is a multiprotein complex required for exocytosis in Saccharomyces cerevisiae. EMBO J 15(23):6483-94
 
  {{SGDpaper|S000047160}} PMID 8978675</ref>
 
  {{SGDpaper|S000047160}} PMID 8978675</ref>
 
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Latest revision as of 07:45, 23 January 2012

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Systematic name YER008C
Gene name SEC3
Aliases PSL1
Feature type ORF, Verified
Coordinates Chr V:171818..167808
Primary SGDID S000000810


Description of YER008C: Subunit of the exocyst complex (Sec3p, Sec5p, Sec6p, Sec8p, Sec10p, Sec15p, Exo70p, Exo84p) which mediates targeting of post-Golgi vesicles to sites of active exocytosis; Sec3p specifically is a spatial landmark for secretion[1][2][3][4]




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Protein Details

Protein Modification

Modification(s): Phosphorylation

Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [5] [6]





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References

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  1. Finger FP and Novick P (1998) Spatial regulation of exocytosis: lessons from yeast. J Cell Biol 142(3):609-12 SGD PMID 9700152
  2. Finger FP, et al. (1998) Sec3p is a spatial landmark for polarized secretion in budding yeast. Cell 92(4):559-71 SGD PMID 9491896
  3. TerBush DR and Novick P (1995) Sec6, Sec8, and Sec15 are components of a multisubunit complex which localizes to small bud tips in Saccharomyces cerevisiae. J Cell Biol 130(2):299-312 SGD PMID 7615633
  4. TerBush DR, et al. (1996) The Exocyst is a multiprotein complex required for exocytosis in Saccharomyces cerevisiae. EMBO J 15(23):6483-94 SGD PMID 8978675
  5. Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
  6. submitted by Jeff Ubersax on 2004-01-27

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