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Systematic name YER008C
Gene name SEC3
Aliases PSL1
Feature type ORF, Verified
Coordinates Chr V:171818..167808
Primary SGDID S000000810

Description of YER008C: Subunit of the exocyst complex (Sec3p, Sec5p, Sec6p, Sec8p, Sec10p, Sec15p, Exo70p, Exo84p) which mediates targeting of post-Golgi vesicles to sites of active exocytosis; Sec3p specifically is a spatial landmark for secretion[1][2][3][4]


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Protein Details

Protein Modification

Modification(s): Phosphorylation

Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [5] [6]



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  1. Finger FP and Novick P (1998) Spatial regulation of exocytosis: lessons from yeast. J Cell Biol 142(3):609-12 SGD PMID 9700152
  2. Finger FP, et al. (1998) Sec3p is a spatial landmark for polarized secretion in budding yeast. Cell 92(4):559-71 SGD PMID 9491896
  3. TerBush DR and Novick P (1995) Sec6, Sec8, and Sec15 are components of a multisubunit complex which localizes to small bud tips in Saccharomyces cerevisiae. J Cell Biol 130(2):299-312 SGD PMID 7615633
  4. TerBush DR, et al. (1996) The Exocyst is a multiprotein complex required for exocytosis in Saccharomyces cerevisiae. EMBO J 15(23):6483-94 SGD PMID 8978675
  5. Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
  6. submitted by Jeff Ubersax on 2004-01-27

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