Difference between revisions of "YER008C"

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'''Description of YER008C:''' Non-essential subunit of the exocyst complex (Sec3p, Sec5p, Sec6p, Sec8p, Sec10p, Sec15p, Exo70p, Exo84p) which mediates targeting of post-Golgi vesicles to sites of active exocytosis; Sec3p specifically is a spatial landmark for secretion<ref name='S000039481'>Finger FP and Novick P (1998) Spatial regulation of exocytosis: lessons from yeast. J Cell Biol 142(3):609-12 {{SGDpaper|S000039481}} PMID 9700152</ref><ref name='S000041326'>Finger FP, et al. (1998) Sec3p is a spatial landmark for polarized secretion in budding yeast. Cell 92(4):559-71 {{SGDpaper|S000041326}} PMID 9491896</ref><ref name='S000047160'>TerBush DR, et al. (1996) The Exocyst is a multiprotein complex required for exocytosis in Saccharomyces cerevisiae. EMBO J 15(23):6483-94
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'''Description of YER008C:''' Non-essential subunit of the exocyst complex (Sec3p, Sec5p, Sec6p, Sec8p, Sec10p, Sec15p, Exo70p, Exo84p) which mediates targeting of post-Golgi vesicles to sites of active exocytosis; Sec3p specifically is a spatial landmark for secretion<ref name='S000047160'>TerBush DR, et al. (1996) The Exocyst is a multiprotein complex required for exocytosis in Saccharomyces cerevisiae. EMBO J 15(23):6483-94 {{SGDpaper|S000047160}} PMID 8978675</ref><ref name='S000041326'>Finger FP, et al. (1998) Sec3p is a spatial landmark for polarized secretion in budding yeast. Cell 92(4):559-71 {{SGDpaper|S000041326}} PMID 9491896</ref><ref name='S000039481'>Finger FP and Novick P (1998) Spatial regulation of exocytosis: lessons from yeast. J Cell Biol 142(3):609-12
  {{SGDpaper|S000047160}} PMID 8978675</ref>
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  {{SGDpaper|S000039481}} PMID 9700152</ref>
 
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Revision as of 14:05, 16 January 2009

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Systematic name YER008C
Gene name SEC3
Aliases PSL1
Feature type ORF, Verified
Coordinates Chr V:171817..167807
Primary SGDID S000000810


Description of YER008C: Non-essential subunit of the exocyst complex (Sec3p, Sec5p, Sec6p, Sec8p, Sec10p, Sec15p, Exo70p, Exo84p) which mediates targeting of post-Golgi vesicles to sites of active exocytosis; Sec3p specifically is a spatial landmark for secretion[1][2][3]




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Protein Details

Protein Modification

Modification(s): Phosphorylation

Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [4] [5]





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References

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  1. TerBush DR, et al. (1996) The Exocyst is a multiprotein complex required for exocytosis in Saccharomyces cerevisiae. EMBO J 15(23):6483-94 SGD PMID 8978675
  2. Finger FP, et al. (1998) Sec3p is a spatial landmark for polarized secretion in budding yeast. Cell 92(4):559-71 SGD PMID 9491896
  3. Finger FP and Novick P (1998) Spatial regulation of exocytosis: lessons from yeast. J Cell Biol 142(3):609-12 SGD PMID 9700152
  4. Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
  5. submitted by Jeff Ubersax on 2004-01-27

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