Difference between revisions of "YER005W"

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'''Description of YER005W:''' Apyrase with wide substrate specificity, involved in preventing the inhibition of glycosylation by hydrolyzing nucleoside tri- and diphosphates which are inhibitors of glycotransferases; partially redundant with Gda1p<ref name='S000045197'>Gao XD, et al. (1999) YND1, a homologue of GDA1, encodes membrane-bound apyrase required for Golgi N- and O-glycosylation in Saccharomyces cerevisiae. J Biol Chem 274(30):21450-6
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'''Description of YER005W:''' Apyrase with wide substrate specificity, helps prevent inhibition of glycosylation by hydrolyzing nucleoside tri- and diphosphates that inhibit glycotransferases; partially redundant with Gda1p; mediates adenovirus E4orf4-induced toxicity<ref name='S000045197'>Gao XD, et al. (1999) YND1, a homologue of GDA1, encodes membrane-bound apyrase required for Golgi N- and O-glycosylation in Saccharomyces cerevisiae. J Biol Chem 274(30):21450-6 {{SGDpaper|S000045197}} PMID 10409709</ref><ref name='S000141161'>Mittelman K, et al. (2010) The Cytosolic Tail of the Golgi Apyrase Ynd1 Mediates E4orf4-Induced Toxicity in Saccharomyces cerevisiae. PLoS One 5(11):e15539
  {{SGDpaper|S000045197}} PMID 10409709</ref>
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  {{SGDpaper|S000141161}} PMID 21124936</ref>
 
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Revision as of 14:05, 23 March 2011

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Systematic name YER005W
Gene name YND1
Aliases YEJ5
Feature type ORF, Verified
Coordinates Chr V:160550..162442
Primary SGDID S000000807


Description of YER005W: Apyrase with wide substrate specificity, helps prevent inhibition of glycosylation by hydrolyzing nucleoside tri- and diphosphates that inhibit glycotransferases; partially redundant with Gda1p; mediates adenovirus E4orf4-induced toxicity[1][2]




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References

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  1. Gao XD, et al. (1999) YND1, a homologue of GDA1, encodes membrane-bound apyrase required for Golgi N- and O-glycosylation in Saccharomyces cerevisiae. J Biol Chem 274(30):21450-6 SGD PMID 10409709
  2. Mittelman K, et al. (2010) The Cytosolic Tail of the Golgi Apyrase Ynd1 Mediates E4orf4-Induced Toxicity in Saccharomyces cerevisiae. PLoS One 5(11):e15539 SGD PMID 21124936

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