YER005W

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Systematic name YER005W
Gene name YND1
Aliases APY1, YEJ5
Feature type ORF, Verified
Coordinates Chr V:160550..162442
Primary SGDID S000000807


Description of YER005W: Apyrase with wide substrate specificity, helps prevent inhibition of glycosylation by hydrolyzing nucleoside tri- and diphosphates that inhibit glycotransferases; partially redundant with Gda1p; mediates adenovirus E4orf4-induced toxicity[1][2]




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References

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  1. Gao XD, et al. (1999) YND1, a homologue of GDA1, encodes membrane-bound apyrase required for Golgi N- and O-glycosylation in Saccharomyces cerevisiae. J Biol Chem 274(30):21450-6 SGD PMID 10409709
  2. Mittelman K, et al. (2010) The Cytosolic Tail of the Golgi Apyrase Ynd1 Mediates E4orf4-Induced Toxicity in Saccharomyces cerevisiae. PLoS One 5(11):e15539 SGD PMID 21124936

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