Difference between revisions of "YEL019C"

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'''Description of YEL019C:''' SUMO ligase involved in chromosomal organization and DNA repair; essential subunit of the Mms21-Smc5-Smc6 complex; mutants are sensitive to methyl methanesulfonate and show increased spontaneous mutation and mitotic recombination<ref name='S000047995'>Prakash S and Prakash L (1977) Increased spontaneous mitotic segregation in MMS-sensitive mutants of Saccharomyces cerevisiae. Genetics 87(2):229-36 {{SGDpaper|S000047995}} PMID 200524</ref><ref name='S000049039'>Montelone BA and Koelliker KJ (1995) Interactions among mutations affecting spontaneous mutation, mitotic recombination, and DNA repair in yeast. Curr Genet 27(2):102-9 {{SGDpaper|S000049039}} PMID 7788712</ref><ref name='S000080949'>Zhao X and Blobel G (2005) A SUMO ligase is part of a nuclear multiprotein complex that affects DNA repair and chromosomal organization. Proc Natl Acad Sci U S A 102(13):4777-82
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'''Description of YEL019C:''' SUMO ligase involved in chromosomal organization and DNA repair; essential subunit of the Mms21-Smc5-Smc6 complex; mutants are sensitive to methyl methanesulfonate and show increased spontaneous mutation and mitotic recombination<ref name='S000080949'>Zhao X and Blobel G (2005) A SUMO ligase is part of a nuclear multiprotein complex that affects DNA repair and chromosomal organization. Proc Natl Acad Sci U S A 102(13):4777-82 {{SGDpaper|S000080949}} PMID 15738391</ref><ref name='S000049039'>Montelone BA and Koelliker KJ (1995) Interactions among mutations affecting spontaneous mutation, mitotic recombination, and DNA repair in yeast. Curr Genet 27(2):102-9 {{SGDpaper|S000049039}} PMID 7788712</ref><ref name='S000047995'>Prakash S and Prakash L (1977) Increased spontaneous mitotic segregation in MMS-sensitive mutants of Saccharomyces cerevisiae. Genetics 87(2):229-36
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  {{SGDpaper|S000047995}} PMID 200524</ref>
 
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Revision as of 14:05, 16 January 2009

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Systematic name YEL019C
Gene name MMS21
Aliases NSE2, PSO10
Feature type ORF, Verified
Coordinates Chr V:121301..120498
Primary SGDID S000000745


Description of YEL019C: SUMO ligase involved in chromosomal organization and DNA repair; essential subunit of the Mms21-Smc5-Smc6 complex; mutants are sensitive to methyl methanesulfonate and show increased spontaneous mutation and mitotic recombination[1][2][3]




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References

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  1. Zhao X and Blobel G (2005) A SUMO ligase is part of a nuclear multiprotein complex that affects DNA repair and chromosomal organization. Proc Natl Acad Sci U S A 102(13):4777-82 SGD PMID 15738391
  2. Montelone BA and Koelliker KJ (1995) Interactions among mutations affecting spontaneous mutation, mitotic recombination, and DNA repair in yeast. Curr Genet 27(2):102-9 SGD PMID 7788712
  3. Prakash S and Prakash L (1977) Increased spontaneous mitotic segregation in MMS-sensitive mutants of Saccharomyces cerevisiae. Genetics 87(2):229-36 SGD PMID 200524

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