Difference between revisions of "YDR379W"

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'''Description of YDR379W:''' GTPase-activating protein for the polarity-establishment protein Cdc42p; implicated in control of septin organization, pheromone response, and haploid invasive growth; regulated by Pho85p and Cdc28p<ref name='S000124082'>Sopko R, et al. (2007) Activation of the Cdc42p GTPase by cyclin-dependent protein kinases in budding yeast. EMBO J 26(21):4487-500 {{SGDpaper|S000124082}} PMID 17853895</ref><ref name='S000072335'>Smith GR, et al. (2002) GTPase-activating proteins for Cdc42. Eukaryot Cell 1(3):469-80
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'''Description of YDR379W:''' GTPase-activating protein for the polarity-establishment protein Cdc42p; implicated in control of septin organization, pheromone response, and haploid invasive growth; regulated by Pho85p and Cdc28p<ref name='S000072335'>Smith GR, et al. (2002) GTPase-activating proteins for Cdc42. Eukaryot Cell 1(3):469-80 {{SGDpaper|S000072335}} PMID 12455995</ref><ref name='S000124082'>Sopko R, et al. (2007) Activation of the Cdc42p GTPase by cyclin-dependent protein kinases in budding yeast. EMBO J 26(21):4487-500
  {{SGDpaper|S000072335}} PMID 12455995</ref>
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  {{SGDpaper|S000124082}} PMID 17853895</ref>
 
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Revision as of 04:15, 19 December 2008

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Systematic name YDR379W
Gene name RGA2
Aliases
Feature type ORF, Verified
Coordinates Chr IV:1230160..1233189
Primary SGDID S000002787


Description of YDR379W: GTPase-activating protein for the polarity-establishment protein Cdc42p; implicated in control of septin organization, pheromone response, and haploid invasive growth; regulated by Pho85p and Cdc28p[1][2]




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Protein Details

Protein Modification

Modification(s): Phosphorylation

Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [3] [4]





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References

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  1. Smith GR, et al. (2002) GTPase-activating proteins for Cdc42. Eukaryot Cell 1(3):469-80 SGD PMID 12455995
  2. Sopko R, et al. (2007) Activation of the Cdc42p GTPase by cyclin-dependent protein kinases in budding yeast. EMBO J 26(21):4487-500 SGD PMID 17853895
  3. Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
  4. submitted by Jeff Ubersax on 2004-01-21

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