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Systematic name YDR379W
Gene name RGA2
Feature type ORF, Verified
Coordinates Chr IV:1230167..1233196
Primary SGDID S000002787

Description of YDR379W: GTPase-activating protein for the polarity-establishment protein Cdc42p; implicated in control of septin organization, pheromone response, and haploid invasive growth; regulated by Pho85p and Cdc28p[1][2]


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Protein Details

Protein Modification

Modification(s): Phosphorylation

Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [3] [4]



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  1. Smith GR, et al. (2002) GTPase-activating proteins for Cdc42. Eukaryot Cell 1(3):469-80 SGD PMID 12455995
  2. Sopko R, et al. (2007) Activation of the Cdc42p GTPase by cyclin-dependent protein kinases in budding yeast. EMBO J 26(21):4487-500 SGD PMID 17853895
  3. Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
  4. submitted by Jeff Ubersax on 2004-01-21

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