Difference between revisions of "YDR363W-A"
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr IV: | + | |nowrap| Chr IV:1202121..1202390 |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000007235 | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000007235 | ||
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| − | '''Description of YDR363W-A:''' Component of the lid subcomplex of the regulatory subunit of the 26S proteasome; ortholog of human DSS1<ref name='S000079881'>Funakoshi M, et al. (2004) Sem1, the yeast ortholog of a human BRCA2-binding protein, is a component of the proteasome regulatory particle that enhances proteasome stability. J Cell Sci 117(Pt 26):6447-54 {{SGDpaper|S000079881}} PMID 15572408</ref><ref name='S000076568'>Sone T, et al. (2004) Sem1p is a novel subunit of the 26 S proteasome from Saccharomyces cerevisiae. J Biol Chem 279(27):28807-16 {{SGDpaper|S000076568}} PMID 15117943</ref><ref name='S000054521'>Jantti J, et al. (1999) SEM1, a homologue of the split hand/split foot malformation candidate gene Dss1, regulates exocytosis and pseudohyphal differentiation in yeast. Proc Natl Acad Sci U S A 96(3):909-14 | + | '''Description of YDR363W-A:''' Component of the lid subcomplex of the regulatory subunit of the 26S proteasome; involved in mRNA export mediated by the TREX-2 complex (Sac3p-Thp1p); ortholog of human DSS1<ref name='S000128899'>Wilmes GM, et al. (2008) A genetic interaction map of RNA-processing factors reveals links between Sem1/Dss1-containing complexes and mRNA export and splicing. Mol Cell 32(5):735-46 {{SGDpaper|S000128899}} PMID 19061648</ref><ref name='S000079881'>Funakoshi M, et al. (2004) Sem1, the yeast ortholog of a human BRCA2-binding protein, is a component of the proteasome regulatory particle that enhances proteasome stability. J Cell Sci 117(Pt 26):6447-54 {{SGDpaper|S000079881}} PMID 15572408</ref><ref name='S000076568'>Sone T, et al. (2004) Sem1p is a novel subunit of the 26 S proteasome from Saccharomyces cerevisiae. J Biol Chem 279(27):28807-16 {{SGDpaper|S000076568}} PMID 15117943</ref><ref name='S000054521'>Jantti J, et al. (1999) SEM1, a homologue of the split hand/split foot malformation candidate gene Dss1, regulates exocytosis and pseudohyphal differentiation in yeast. Proc Natl Acad Sci U S A 96(3):909-14 |
{{SGDpaper|S000054521}} PMID 9927667</ref> | {{SGDpaper|S000054521}} PMID 9927667</ref> | ||
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Revision as of 07:21, 26 February 2009
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| Systematic name | YDR363W-A |
| Gene name | SEM1 |
| Aliases | DSS1, HOD1 |
| Feature type | ORF, Verified |
| Coordinates | Chr IV:1202121..1202390 |
| Primary SGDID | S000007235 |
Description of YDR363W-A: Component of the lid subcomplex of the regulatory subunit of the 26S proteasome; involved in mRNA export mediated by the TREX-2 complex (Sac3p-Thp1p); ortholog of human DSS1[1][2][3][4]
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References
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- ↑ Wilmes GM, et al. (2008) A genetic interaction map of RNA-processing factors reveals links between Sem1/Dss1-containing complexes and mRNA export and splicing. Mol Cell 32(5):735-46 SGD PMID 19061648
- ↑ Funakoshi M, et al. (2004) Sem1, the yeast ortholog of a human BRCA2-binding protein, is a component of the proteasome regulatory particle that enhances proteasome stability. J Cell Sci 117(Pt 26):6447-54 SGD PMID 15572408
- ↑ Sone T, et al. (2004) Sem1p is a novel subunit of the 26 S proteasome from Saccharomyces cerevisiae. J Biol Chem 279(27):28807-16 SGD PMID 15117943
- ↑ Jantti J, et al. (1999) SEM1, a homologue of the split hand/split foot malformation candidate gene Dss1, regulates exocytosis and pseudohyphal differentiation in yeast. Proc Natl Acad Sci U S A 96(3):909-14 SGD PMID 9927667
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