Difference between revisions of "YDR356W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr IV:1186100..1188934
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|nowrap| Chr IV:1186101..1188935
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000002764
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000002764

Revision as of 14:05, 5 June 2008

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Systematic name YDR356W
Gene name SPC110
Aliases NUF1, XCM1
Feature type ORF, Verified
Coordinates Chr IV:1186101..1188935
Primary SGDID S000002764


Description of YDR356W: Inner plaque spindle pole body (SPB) component, ortholog of human kendrin; involved in connecting nuclear microtubules to SPB; interacts with Tub4p-complex and calmodulin; phosphorylated by Mps1p in cell cycle-dependent manner[1][2][3][4][5]




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References

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  1. Friedman DB, et al. (2001) Yeast Mps1p phosphorylates the spindle pole component Spc110p in the N-terminal domain. J Biol Chem 276(21):17958-67 SGD PMID 11278681
  2. Knop M and Schiebel E (1997) Spc98p and Spc97p of the yeast gamma-tubulin complex mediate binding to the spindle pole body via their interaction with Spc110p. EMBO J 16(23):6985-95 SGD PMID 9384578
  3. Mirzayan C, et al. (1992) The NUF1 gene encodes an essential coiled-coil related protein that is a potential component of the yeast nucleoskeleton. J Cell Biol 116(6):1319-32 SGD PMID 1541631
  4. Flory MR, et al. (2000) Identification of a human centrosomal calmodulin-binding protein that shares homology with pericentrin. Proc Natl Acad Sci U S A 97(11):5919-23 SGD PMID 10823944
  5. Geiser JR, et al. (1993) The essential mitotic target of calmodulin is the 110-kilodalton component of the spindle pole body in Saccharomyces cerevisiae. Mol Cell Biol 13(12):7913-24 SGD PMID 8247006

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