Difference between revisions of "YDR309C"

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'''Description of YDR309C:''' Redundant rho-like GTPase Cdc42p effector; homolog of Gic1p; involved in initiation of budding and cellular polarization; interacts with Cdc42p via the Cdc42/Rac-interactive binding (CRIB) domain and with PI(4,5)P2 via a polybasic region<ref name='S000053861'>Chen GC, et al. (1997) The Cdc42 GTPase-associated proteins Gic1 and Gic2 are required for polarized cell growth in Saccharomyces cerevisiae. Genes Dev 11(22):2958-71 {{SGDpaper|S000053861}} PMID 9367979</ref><ref name='S000053873'>Brown JL, et al. (1997) Novel Cdc42-binding proteins Gic1 and Gic2 control cell polarity in yeast. Genes Dev 11(22):2972-82 {{SGDpaper|S000053873}} PMID 9367980</ref><ref name='S000072871'>Kawasaki R, et al. (2003) The upstream regulator, Rsr1p, and downstream effectors, Gic1p and Gic2p, of the Cdc42p small GTPase coordinately regulate initiation of budding in Saccharomyces cerevisiae. Genes Cells 8(3):235-50 {{SGDpaper|S000072871}} PMID 12622721</ref><ref name='S000125995'>Orlando K, et al. (2008) Regulation of Gic2 Localization and Function by Phosphatidylinositol 4,5-Bisphosphate during the Establishment of Cell Polarity in Budding Yeast. J Biol Chem 283(21):14205-12
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'''Description of YDR309C:''' Redundant rho-like GTPase Cdc42p effector; homolog of Gic1p; involved in initiation of budding and cellular polarization; interacts with Cdc42p via the Cdc42/Rac-interactive binding (CRIB) domain and with PI(4,5)P2 via a polybasic region<ref name='S000125995'>Orlando K, et al. (2008) Regulation of Gic2 Localization and Function by Phosphatidylinositol 4,5-Bisphosphate during the Establishment of Cell Polarity in Budding Yeast. J Biol Chem 283(21):14205-12 {{SGDpaper|S000125995}} PMID 18387956</ref><ref name='S000072871'>Kawasaki R, et al. (2003) The upstream regulator, Rsr1p, and downstream effectors, Gic1p and Gic2p, of the Cdc42p small GTPase coordinately regulate initiation of budding in Saccharomyces cerevisiae. Genes Cells 8(3):235-50 {{SGDpaper|S000072871}} PMID 12622721</ref><ref name='S000053873'>Brown JL, et al. (1997) Novel Cdc42-binding proteins Gic1 and Gic2 control cell polarity in yeast. Genes Dev 11(22):2972-82 {{SGDpaper|S000053873}} PMID 9367980</ref><ref name='S000053861'>Chen GC, et al. (1997) The Cdc42 GTPase-associated proteins Gic1 and Gic2 are required for polarized cell growth in Saccharomyces cerevisiae. Genes Dev 11(22):2958-71
  {{SGDpaper|S000125995}} PMID 18387956</ref>
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  {{SGDpaper|S000053861}} PMID 9367979</ref>
 
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Revision as of 14:05, 16 January 2009

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Systematic name YDR309C
Gene name GIC2
Aliases
Feature type ORF, Verified
Coordinates Chr IV:1080196..1079045
Primary SGDID S000002717


Description of YDR309C: Redundant rho-like GTPase Cdc42p effector; homolog of Gic1p; involved in initiation of budding and cellular polarization; interacts with Cdc42p via the Cdc42/Rac-interactive binding (CRIB) domain and with PI(4,5)P2 via a polybasic region[1][2][3][4]




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DNA and RNA Details

Other DNA and RNA Details

Other Topic: expression

Specifically lower expression in carbon limited chemostat cultures versus carbon excess. [5] [6]





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References

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  1. Orlando K, et al. (2008) Regulation of Gic2 Localization and Function by Phosphatidylinositol 4,5-Bisphosphate during the Establishment of Cell Polarity in Budding Yeast. J Biol Chem 283(21):14205-12 SGD PMID 18387956
  2. Kawasaki R, et al. (2003) The upstream regulator, Rsr1p, and downstream effectors, Gic1p and Gic2p, of the Cdc42p small GTPase coordinately regulate initiation of budding in Saccharomyces cerevisiae. Genes Cells 8(3):235-50 SGD PMID 12622721
  3. Brown JL, et al. (1997) Novel Cdc42-binding proteins Gic1 and Gic2 control cell polarity in yeast. Genes Dev 11(22):2972-82 SGD PMID 9367980
  4. Chen GC, et al. (1997) The Cdc42 GTPase-associated proteins Gic1 and Gic2 are required for polarized cell growth in Saccharomyces cerevisiae. Genes Dev 11(22):2958-71 SGD PMID 9367979
  5. Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. J Biol Chem 278(5):3265-74 SGD PMID 12414795
  6. submitted by Viktor Boer on 2003-07-25

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