YDR309C
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| Systematic name | YDR309C |
| Gene name | GIC2 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr IV:1080199..1079048 |
| Primary SGDID | S000002717 |
Description of YDR309C: Redundant rho-like GTPase Cdc42p effector; homolog of Gic1p; involved in initiation of budding and cellular polarization; interacts with Cdc42p via the Cdc42/Rac-interactive binding (CRIB) domain and with PI(4,5)P2 via a polybasic region[1][2][3][4]
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Community Commentary
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DNA and RNA Details
Other DNA and RNA Details
Other Topic: expression
Specifically lower expression in carbon limited chemostat cultures versus carbon excess. [5] [6]
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References
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- ↑ Brown JL, et al. (1997) Novel Cdc42-binding proteins Gic1 and Gic2 control cell polarity in yeast. Genes Dev 11(22):2972-82 SGD PMID 9367980
- ↑ Chen GC, et al. (1997) The Cdc42 GTPase-associated proteins Gic1 and Gic2 are required for polarized cell growth in Saccharomyces cerevisiae. Genes Dev 11(22):2958-71 SGD PMID 9367979
- ↑ Kawasaki R, et al. (2003) The upstream regulator, Rsr1p, and downstream effectors, Gic1p and Gic2p, of the Cdc42p small GTPase coordinately regulate initiation of budding in Saccharomyces cerevisiae. Genes Cells 8(3):235-50 SGD PMID 12622721
- ↑ Orlando K, et al. (2008) Regulation of Gic2 Localization and Function by Phosphatidylinositol 4,5-Bisphosphate during the Establishment of Cell Polarity in Budding Yeast. J Biol Chem 283(21):14205-12 SGD PMID 18387956
- ↑ Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. J Biol Chem 278(5):3265-74 SGD PMID 12414795
- ↑ submitted by Viktor Boer on 2003-07-25
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