Difference between revisions of "YDR213W"

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'''Description of YDR213W:''' Sterol regulatory element binding protein, induces transcription of sterol transport and biosynthetic genes; involved in the anaerobic induction of DAN/TIR mannoproteins and seripauperins; binucleate zinc cluster protein; Ecm22p homolog<ref name='S000071132'>Wilcox LJ, et al. (2002) Transcriptional profiling identifies two members of the ATP-binding cassette transporter superfamily required for sterol uptake in yeast. J Biol Chem 277(36):32466-72 {{SGDpaper|S000071132}} PMID 12077145</ref><ref name='S000069102'>Kwast KE, et al. (2002) Genomic analyses of anaerobically induced genes in Saccharomyces cerevisiae: functional roles of Rox1 and other factors in mediating the anoxic response. J Bacteriol 184(1):250-65 {{SGDpaper|S000069102}} PMID 11741867</ref><ref name='S000066114'>Vik A and Rine J (2001) Upc2p and Ecm22p, dual regulators of sterol biosynthesis in Saccharomyces cerevisiae. Mol Cell Biol 21(19):6395-405 {{SGDpaper|S000066114}} PMID 11533229</ref><ref name='S000060147'>Abramova N, et al. (2001) Reciprocal regulation of anaerobic and aerobic cell wall mannoprotein gene expression in Saccharomyces cerevisiae. J Bacteriol 183(9):2881-7 {{SGDpaper|S000060147}} PMID 11292809</ref><ref name='S000060061'>Abramova NE, et al. (2001) Regulatory mechanisms controlling expression of the DAN/TIR mannoprotein genes during anaerobic remodeling of the cell wall in Saccharomyces cerevisiae. Genetics 157(3):1169-77 {{SGDpaper|S000060061}} PMID 11238402</ref><ref name='S000059529'>Shianna KV, et al. (2001) Identification of a UPC2 homolog in Saccharomyces cerevisiae and its involvement in aerobic sterol uptake. J Bacteriol 183(3):830-4 {{SGDpaper|S000059529}} PMID 11208779</ref><ref name='S000042754'>Crowley JH, et al. (1998) A mutation in a purported regulatory gene affects control of sterol uptake in Saccharomyces cerevisiae. J Bacteriol 180(16):4177-83
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'''Description of YDR213W:''' Sterol regulatory element binding protein, induces transcription of sterol biosynthetic genes and of DAN/TIR gene products; Ecm22p homolog; relocates from intracellular membranes to perinuclear foci on sterol depletion<ref name='S000127297'>Marie C, et al. (2008) Cytoplasmic localization of sterol transcription factors Upc2p and Ecm22p in S. cerevisiae. Fungal Genet Biol  {{SGDpaper|S000127297}} PMID 18675371</ref><ref name='S000071132'>Wilcox LJ, et al. (2002) Transcriptional profiling identifies two members of the ATP-binding cassette transporter superfamily required for sterol uptake in yeast. J Biol Chem 277(36):32466-72 {{SGDpaper|S000071132}} PMID 12077145</ref><ref name='S000069102'>Kwast KE, et al. (2002) Genomic analyses of anaerobically induced genes in Saccharomyces cerevisiae: functional roles of Rox1 and other factors in mediating the anoxic response. J Bacteriol 184(1):250-65 {{SGDpaper|S000069102}} PMID 11741867</ref><ref name='S000066114'>Vik A and Rine J (2001) Upc2p and Ecm22p, dual regulators of sterol biosynthesis in Saccharomyces cerevisiae. Mol Cell Biol 21(19):6395-405 {{SGDpaper|S000066114}} PMID 11533229</ref><ref name='S000060147'>Abramova N, et al. (2001) Reciprocal regulation of anaerobic and aerobic cell wall mannoprotein gene expression in Saccharomyces cerevisiae. J Bacteriol 183(9):2881-7 {{SGDpaper|S000060147}} PMID 11292809</ref><ref name='S000060061'>Abramova NE, et al. (2001) Regulatory mechanisms controlling expression of the DAN/TIR mannoprotein genes during anaerobic remodeling of the cell wall in Saccharomyces cerevisiae. Genetics 157(3):1169-77 {{SGDpaper|S000060061}} PMID 11238402</ref><ref name='S000059529'>Shianna KV, et al. (2001) Identification of a UPC2 homolog in Saccharomyces cerevisiae and its involvement in aerobic sterol uptake. J Bacteriol 183(3):830-4 {{SGDpaper|S000059529}} PMID 11208779</ref><ref name='S000042754'>Crowley JH, et al. (1998) A mutation in a purported regulatory gene affects control of sterol uptake in Saccharomyces cerevisiae. J Bacteriol 180(16):4177-83
 
  {{SGDpaper|S000042754}} PMID 9696767</ref>
 
  {{SGDpaper|S000042754}} PMID 9696767</ref>
 
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Revision as of 14:05, 19 September 2008

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Systematic name YDR213W
Gene name UPC2
Aliases MOX4
Feature type ORF, Verified
Coordinates Chr IV:889749..892490
Primary SGDID S000002621


Description of YDR213W: Sterol regulatory element binding protein, induces transcription of sterol biosynthetic genes and of DAN/TIR gene products; Ecm22p homolog; relocates from intracellular membranes to perinuclear foci on sterol depletion[1][2][3][4][5][6][7][8]




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References

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  1. Marie C, et al. (2008) Cytoplasmic localization of sterol transcription factors Upc2p and Ecm22p in S. cerevisiae. Fungal Genet Biol SGD PMID 18675371
  2. Wilcox LJ, et al. (2002) Transcriptional profiling identifies two members of the ATP-binding cassette transporter superfamily required for sterol uptake in yeast. J Biol Chem 277(36):32466-72 SGD PMID 12077145
  3. Kwast KE, et al. (2002) Genomic analyses of anaerobically induced genes in Saccharomyces cerevisiae: functional roles of Rox1 and other factors in mediating the anoxic response. J Bacteriol 184(1):250-65 SGD PMID 11741867
  4. Vik A and Rine J (2001) Upc2p and Ecm22p, dual regulators of sterol biosynthesis in Saccharomyces cerevisiae. Mol Cell Biol 21(19):6395-405 SGD PMID 11533229
  5. Abramova N, et al. (2001) Reciprocal regulation of anaerobic and aerobic cell wall mannoprotein gene expression in Saccharomyces cerevisiae. J Bacteriol 183(9):2881-7 SGD PMID 11292809
  6. Abramova NE, et al. (2001) Regulatory mechanisms controlling expression of the DAN/TIR mannoprotein genes during anaerobic remodeling of the cell wall in Saccharomyces cerevisiae. Genetics 157(3):1169-77 SGD PMID 11238402
  7. Shianna KV, et al. (2001) Identification of a UPC2 homolog in Saccharomyces cerevisiae and its involvement in aerobic sterol uptake. J Bacteriol 183(3):830-4 SGD PMID 11208779
  8. Crowley JH, et al. (1998) A mutation in a purported regulatory gene affects control of sterol uptake in Saccharomyces cerevisiae. J Bacteriol 180(16):4177-83 SGD PMID 9696767

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