YDR213W

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Systematic name YDR213W
Gene name UPC2
Aliases MOX4
Feature type ORF, Verified
Coordinates Chr IV:889751..892492
Primary SGDID S000002621


Description of YDR213W: Sterol regulatory element binding protein, induces transcription of sterol biosynthetic genes and of DAN/TIR gene products; Ecm22p homolog; relocates from intracellular membranes to perinuclear foci on sterol depletion[1][2][3][4][5][6][7][8]




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References

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  1. Abramova N, et al. (2001) Reciprocal regulation of anaerobic and aerobic cell wall mannoprotein gene expression in Saccharomyces cerevisiae. J Bacteriol 183(9):2881-7 SGD PMID 11292809
  2. Abramova NE, et al. (2001) Regulatory mechanisms controlling expression of the DAN/TIR mannoprotein genes during anaerobic remodeling of the cell wall in Saccharomyces cerevisiae. Genetics 157(3):1169-77 SGD PMID 11238402
  3. Crowley JH, et al. (1998) A mutation in a purported regulatory gene affects control of sterol uptake in Saccharomyces cerevisiae. J Bacteriol 180(16):4177-83 SGD PMID 9696767
  4. Kwast KE, et al. (2002) Genomic analyses of anaerobically induced genes in Saccharomyces cerevisiae: functional roles of Rox1 and other factors in mediating the anoxic response. J Bacteriol 184(1):250-65 SGD PMID 11741867
  5. Marie C, et al. (2008) Cytoplasmic localization of sterol transcription factors Upc2p and Ecm22p in S. cerevisiae. Fungal Genet Biol 45(10):1430-8 SGD PMID 18675371
  6. Shianna KV, et al. (2001) Identification of a UPC2 homolog in Saccharomyces cerevisiae and its involvement in aerobic sterol uptake. J Bacteriol 183(3):830-4 SGD PMID 11208779
  7. Vik A and Rine J (2001) Upc2p and Ecm22p, dual regulators of sterol biosynthesis in Saccharomyces cerevisiae. Mol Cell Biol 21(19):6395-405 SGD PMID 11533229
  8. Wilcox LJ, et al. (2002) Transcriptional profiling identifies two members of the ATP-binding cassette transporter superfamily required for sterol uptake in yeast. J Biol Chem 277(36):32466-72 SGD PMID 12077145

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