YDR143C
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| Systematic name | YDR143C | |
| Gene name | SAN1 | |
| Aliases | ||
| Feature type | ORF, Verified | |
| Coordinates | Chr IV:743871..742039 | |
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Description of YDR143C: Ubiquitin-protein ligase, involved in the proteasome-dependent degradation of aberrant nuclear proteins; san1 mutations suppress sir4, spt16, and cdc68 mutations, suggesting a role in chromatin silencing[1][2][3][4]
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References
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- ↑ Gardner RG, et al. (2005) Degradation-mediated protein quality control in the nucleus. Cell 120(6):803-15 SGD PMID 15797381
- ↑ Dasgupta A, et al. (2004) Sir Antagonist 1 (San1) is a ubiquitin ligase. J Biol Chem 279(26):26830-8 SGD PMID 15078868
- ↑ Xu Q, et al. (1993) The Saccharomyces cerevisiae Cdc68 transcription activator is antagonized by San1, a protein implicated in transcriptional silencing. Mol Cell Biol 13(12):7553-65 SGD PMID 8246972
- ↑ Schnell R, et al. (1989) Genetic and molecular characterization of suppressors of SIR4 mutations in Saccharomyces cerevisiae. Genetics 122(1):29-46 SGD PMID 2471670
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