Difference between revisions of "YDR143C"

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=== Protein Details ===
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Nuclear-localized ubiquitin-protein ligase involved in the proteasome-dependent quality control degradation of aberrant nuclear proteins, including sir4-9, cdc68-1, sir3-8, and cdc13-1. <ref name='S000081200'>Gardner RG, et al. (2005) Degradation-mediated protein quality control in the nucleus. Cell 120(6):803-15 {{SGDpaper|S000081200}} PMID 15797381</ref> <ref name = 'CAset1943-2005-11-09'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=1943 Richard G. Gardner] on 2005-11-09</ref>
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==Community Commentary==
 
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=== Protein Details ===
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==== Protein Function/Process ====
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Nuclear-localized ubiquitin-protein ligase involved in the proteasome-dependent quality control degradation of aberrant nuclear proteins, including sir4-9, cdc68-1, sir3-8, and cdc13-1. <ref name='S000081200'>Gardner RG, et al. (2005) Degradation-mediated protein quality control in the nucleus. Cell 120(6):803-15 {{SGDpaper|S000081200}} PMID 15797381</ref> <ref name = 'CAset1943-2005-11-09'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=1943 Richard G. Gardner] on 2005-11-09</ref>
  
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==References==
 
==References==
 
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Revision as of 17:05, 23 January 2007

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Systematic name YDR143C
Gene name SAN1
Aliases
Feature type ORF, Verified
Coordinates Chr IV:743871..742039
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Description of YDR143C: Ubiquitin-protein ligase, involved in the proteasome-dependent degradation of aberrant nuclear proteins; san1 mutations suppress sir4, spt16, and cdc68 mutations, suggesting a role in chromatin silencing[1][2][3][4]



Protein Details

Protein Function/Process

Nuclear-localized ubiquitin-protein ligase involved in the proteasome-dependent quality control degradation of aberrant nuclear proteins, including sir4-9, cdc68-1, sir3-8, and cdc13-1. [1] [5]


Community Commentary

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Protein Details

Protein Function/Process

Nuclear-localized ubiquitin-protein ligase involved in the proteasome-dependent quality control degradation of aberrant nuclear proteins, including sir4-9, cdc68-1, sir3-8, and cdc13-1. [1] [5]


References

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  1. 1.0 1.1 1.2 Gardner RG, et al. (2005) Degradation-mediated protein quality control in the nucleus. Cell 120(6):803-15 SGD PMID 15797381
  2. Dasgupta A, et al. (2004) Sir Antagonist 1 (San1) is a ubiquitin ligase. J Biol Chem 279(26):26830-8 SGD PMID 15078868
  3. Xu Q, et al. (1993) The Saccharomyces cerevisiae Cdc68 transcription activator is antagonized by San1, a protein implicated in transcriptional silencing. Mol Cell Biol 13(12):7553-65 SGD PMID 8246972
  4. Schnell R, et al. (1989) Genetic and molecular characterization of suppressors of SIR4 mutations in Saccharomyces cerevisiae. Genetics 122(1):29-46 SGD PMID 2471670
  5. 5.0 5.1 submitted by Richard G. Gardner on 2005-11-09

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