Difference between revisions of "YDR130C"

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'''Description of YDR130C:''' Spindle pole body-related intermediate filament protein, forms cell cycle-specific filaments between spindle pole bodies in mother and daughter cells, able to self-assemble, expression induced during S/G2, localization cell-cycle dependent<ref name='S000069577'>van Hemert MJ, et al. (2002) The Saccharomyces cerevisiae Fin1 protein forms cell cycle-specific filaments between spindle pole bodies. Proc Natl Acad Sci U S A 99(8):5390-3 {{SGDpaper|S000069577}} PMID 11929974</ref><ref name='S000070060'>Mayordomo I and Sanz P (2002) The Saccharomyces cerevisiae 14-3-3 protein Bmh2 is required for regulation of the phosphorylation status of Fin1, a novel intermediate filament protein. Biochem J 365(Pt 1):51-6 {{SGDpaper|S000070060}} PMID 11931638</ref><ref name='S000073072'>van Hemert MJ, et al. (2003) Self-association of the spindle pole body-related intermediate filament protein Fin1p and its phosphorylation-dependent interaction with 14-3-3 proteins in yeast. J Biol Chem 278(17):15049-55
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'''Description of YDR130C:''' Spindle pole body-related intermediate filament protein, forms cell cycle-specific filaments between spindle pole bodies in mother and daughter cells, able to self-assemble, expression induced during S/G2, localization cell-cycle dependent<ref name='S000073072'>van Hemert MJ, et al. (2003) Self-association of the spindle pole body-related intermediate filament protein Fin1p and its phosphorylation-dependent interaction with 14-3-3 proteins in yeast. J Biol Chem 278(17):15049-55 {{SGDpaper|S000073072}} PMID 12551942</ref><ref name='S000070060'>Mayordomo I and Sanz P (2002) The Saccharomyces cerevisiae 14-3-3 protein Bmh2 is required for regulation of the phosphorylation status of Fin1, a novel intermediate filament protein. Biochem J 365(Pt 1):51-6 {{SGDpaper|S000070060}} PMID 11931638</ref><ref name='S000069577'>van Hemert MJ, et al. (2002) The Saccharomyces cerevisiae Fin1 protein forms cell cycle-specific filaments between spindle pole bodies. Proc Natl Acad Sci U S A 99(8):5390-3
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  {{SGDpaper|S000069577}} PMID 11929974</ref>
 
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Revision as of 14:05, 16 January 2009

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Systematic name YDR130C
Gene name FIN1
Aliases
Feature type ORF, Verified
Coordinates Chr IV:716620..715745
Primary SGDID S000002537


Description of YDR130C: Spindle pole body-related intermediate filament protein, forms cell cycle-specific filaments between spindle pole bodies in mother and daughter cells, able to self-assemble, expression induced during S/G2, localization cell-cycle dependent[1][2][3]




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Protein Details

Protein Modification

Modification(s): Glycosylation

Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [4] [5]





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References

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  1. van Hemert MJ, et al. (2003) Self-association of the spindle pole body-related intermediate filament protein Fin1p and its phosphorylation-dependent interaction with 14-3-3 proteins in yeast. J Biol Chem 278(17):15049-55 SGD PMID 12551942
  2. Mayordomo I and Sanz P (2002) The Saccharomyces cerevisiae 14-3-3 protein Bmh2 is required for regulation of the phosphorylation status of Fin1, a novel intermediate filament protein. Biochem J 365(Pt 1):51-6 SGD PMID 11931638
  3. van Hemert MJ, et al. (2002) The Saccharomyces cerevisiae Fin1 protein forms cell cycle-specific filaments between spindle pole bodies. Proc Natl Acad Sci U S A 99(8):5390-3 SGD PMID 11929974
  4. Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
  5. submitted by Jeff Ubersax on 2004-01-21

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