Difference between revisions of "YDR108W"

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'''Description of YDR108W:''' Subunit of TRAPP (transport protein particle), a multi-subunit complex involved in targeting and/or fusion of ER-to-Golgi transport vesicles with their acceptor compartment; protein has late meiotic role, following DNA replication<ref name='S000039264'>Engebrecht J, et al. (1998) Yeast meiotic mutants proficient for the induction of ectopic recombination. Genetics 148(2):581-98 {{SGDpaper|S000039264}} PMID 9504908</ref><ref name='S000045171'>Kaytor MD and Livingston DM (1995) GSG1, a yeast gene required for sporulation. Yeast 11(12):1147-55 {{SGDpaper|S000045171}} PMID 8619313</ref><ref name='S000043703'>Sacher M, et al. (2000) Identification and characterization of five new subunits of TRAPP. Eur J Cell Biol 79(2):71-80
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'''Description of YDR108W:''' Subunit of TRAPPIII (transport protein particle), a multimeric guanine nucleotide-exchange factor for Ypt1p, required for membrane expansion during autophagy and the CVT pathway; directs Ypt1p to the PAS; late post-replication meiotic role<ref name='S000039264'>Engebrecht J, et al. (1998) Yeast meiotic mutants proficient for the induction of ectopic recombination. Genetics 148(2):581-98 {{SGDpaper|S000039264}} PMID 9504908</ref><ref name='S000045171'>Kaytor MD and Livingston DM (1995) GSG1, a yeast gene required for sporulation. Yeast 11(12):1147-55 {{SGDpaper|S000045171}} PMID 8619313</ref><ref name='S000134404'>Lynch-Day MA, et al. (2010) Trs85 directs a Ypt1 GEF, TRAPPIII, to the phagophore to promote autophagy. Proc Natl Acad Sci U S A 107(17):7811-6 {{SGDpaper|S000134404}} PMID 20375281</ref><ref name='S000086066'>Meiling-Wesse K, et al. (2005) Trs85 (Gsg1), a component of the TRAPP complexes, is required for the organization of the preautophagosomal structure during selective autophagy via the Cvt pathway. J Biol Chem 280(39):33669-78 {{SGDpaper|S000086066}} PMID 16079147</ref><ref name='S000117385'>Nazarko TY, et al. (2005) Trs85 is required for macroautophagy, pexophagy and cytoplasm to vacuole targeting in Yarrowia lipolytica and Saccharomyces cerevisiae. Autophagy 1(1):37-45
  {{SGDpaper|S000043703}} PMID 10727015</ref>
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  {{SGDpaper|S000117385}} PMID 16874038</ref>
 
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Revision as of 14:05, 30 November 2010

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Systematic name YDR108W
Gene name GSG1
Aliases MUM1, TRS85
Feature type ORF, Verified
Coordinates Chr IV:671267..673363
Primary SGDID S000002515


Description of YDR108W: Subunit of TRAPPIII (transport protein particle), a multimeric guanine nucleotide-exchange factor for Ypt1p, required for membrane expansion during autophagy and the CVT pathway; directs Ypt1p to the PAS; late post-replication meiotic role[1][2][3][4][5]




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References

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  1. Engebrecht J, et al. (1998) Yeast meiotic mutants proficient for the induction of ectopic recombination. Genetics 148(2):581-98 SGD PMID 9504908
  2. Kaytor MD and Livingston DM (1995) GSG1, a yeast gene required for sporulation. Yeast 11(12):1147-55 SGD PMID 8619313
  3. Lynch-Day MA, et al. (2010) Trs85 directs a Ypt1 GEF, TRAPPIII, to the phagophore to promote autophagy. Proc Natl Acad Sci U S A 107(17):7811-6 SGD PMID 20375281
  4. Meiling-Wesse K, et al. (2005) Trs85 (Gsg1), a component of the TRAPP complexes, is required for the organization of the preautophagosomal structure during selective autophagy via the Cvt pathway. J Biol Chem 280(39):33669-78 SGD PMID 16079147
  5. Nazarko TY, et al. (2005) Trs85 is required for macroautophagy, pexophagy and cytoplasm to vacuole targeting in Yarrowia lipolytica and Saccharomyces cerevisiae. Autophagy 1(1):37-45 SGD PMID 16874038

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