YDR108W
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| Systematic name | YDR108W |
| Gene name | TRS85 |
| Aliases | GSG1, MUM1 |
| Feature type | ORF, Verified |
| Coordinates | Chr IV:671269..673365 |
| Primary SGDID | S000002515 |
Description of YDR108W: Subunit of TRAPPIII (transport protein particle), a multimeric guanine nucleotide-exchange factor for Ypt1p, required for membrane expansion during autophagy and the CVT pathway; directs Ypt1p to the PAS; late post-replication meiotic role[1][2][3][4][5]
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References
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- ↑ Engebrecht J, et al. (1998) Yeast meiotic mutants proficient for the induction of ectopic recombination. Genetics 148(2):581-98 SGD PMID 9504908
- ↑ Kaytor MD and Livingston DM (1995) GSG1, a yeast gene required for sporulation. Yeast 11(12):1147-55 SGD PMID 8619313
- ↑ Lynch-Day MA, et al. (2010) Trs85 directs a Ypt1 GEF, TRAPPIII, to the phagophore to promote autophagy. Proc Natl Acad Sci U S A 107(17):7811-6 SGD PMID 20375281
- ↑ Meiling-Wesse K, et al. (2005) Trs85 (Gsg1), a component of the TRAPP complexes, is required for the organization of the preautophagosomal structure during selective autophagy via the Cvt pathway. J Biol Chem 280(39):33669-78 SGD PMID 16079147
- ↑ Nazarko TY, et al. (2005) Trs85 is required for macroautophagy, pexophagy and cytoplasm to vacuole targeting in Yarrowia lipolytica and Saccharomyces cerevisiae. Autophagy 1(1):37-45 SGD PMID 16874038
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