Difference between revisions of "YDR002W"

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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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Revision as of 13:02, 21 February 2007

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Systematic name YDR002W
Gene name YRB1
Aliases CST20, HTN1, SFO1
Feature type ORF, Verified
Coordinates Chr IV:453042..453647


Description of YDR002W: Ran GTpase binding protein; involved in nuclear protein import and RNA export, ubiquitin-mediated protein degradation during the cell cycle; shuttles between the nucleus and cytoplasm; is essential; homolog of human RanBP1[1][2][3][4][5][6]




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References

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  1. Kunzler M, et al. (2001) Mutations in the YRB1 gene encoding yeast ran-binding-protein-1 that impair nucleocytoplasmic transport and suppress yeast mating defects. Genetics 157(3):1089-105 SGD PMID 11238397
  2. Baumer M, et al. (2000) Yeast Ran-binding protein Yrb1p is required for efficient proteolysis of cell cycle regulatory proteins Pds1p and Sic1p. J Biol Chem 275(49):38929-37 SGD PMID 10991951
  3. Schlenstedt G, et al. (1995) Mutants in a yeast Ran binding protein are defective in nuclear transport. EMBO J 14(21):5367-78 SGD PMID 7489726
  4. Ouspenski II, et al. (1995) Ran-binding protein-1 is an essential component of the Ran/RCC1 molecular switch system in budding yeast. J Biol Chem 270(5):1975-8 SGD PMID 7836422
  5. Kunzler M, et al. (2000) Yeast Ran-binding protein 1 (Yrb1) shuttles between the nucleus and cytoplasm and is exported from the nucleus via a CRM1 (XPO1)-dependent pathway. Mol Cell Biol 20(12):4295-308 SGD PMID 10825193
  6. Dingwall C, et al. (1995) A family of Ran binding proteins that includes nucleoporins. Proc Natl Acad Sci U S A 92(16):7525-9 SGD PMID 7638224

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