YDL207W
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| Systematic name | YDL207W |
| Gene name | GLE1 |
| Aliases | BRR3, RSS1 |
| Feature type | ORF, Verified |
| Coordinates | Chr IV:88248..89864 |
| Primary SGDID | S000002366 |
Description of YDL207W: Cytoplasmic nucleoporin required for polyadenylated RNA export; not essential for protein import; contains a nuclear export signal; when bound to inositol hexakisphosphate (IP6), functions as an activator for the ATPase activity of Dbp1p at the nuclear pore complex during mRNA export[1][2][3][4]
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References
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- ↑ Alcazar-Roman AR, et al. (2006) Inositol hexakisphosphate and Gle1 activate the DEAD-box protein Dbp5 for nuclear mRNA export. Nat Cell Biol 8(7):711-6 SGD PMID 16783363
- ↑ Del Priore V, et al. (1996) The product of the Saccharomyces cerevisiae RSS1 gene, identified as a high-copy suppressor of the rat7-1 temperature-sensitive allele of the RAT7/NUP159 nucleoporin, is required for efficient mRNA export. Mol Biol Cell 7(10):1601-21 SGD PMID 8898365
- ↑ Hurwitz ME, et al. (1998) Two yeast nuclear pore complex proteins involved in mRNA export form a cytoplasmically oriented subcomplex. Proc Natl Acad Sci U S A 95(19):11241-5 SGD PMID 9736720
- ↑ Murphy R and Wente SR (1996) An RNA-export mediator with an essential nuclear export signal. Nature 383(6598):357-60 SGD PMID 8848052
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