YDL194W

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Systematic name YDL194W
Gene name SNF3
Aliases
Feature type ORF, Verified
Coordinates Chr IV:111581..114235


Description of YDL194W: Plasma membrane glucose sensor that regulates glucose transport; has 12 predicted transmembrane segments; long cytoplasmic C-terminal tail is required for low glucose induction of hexose transporter genes HXT2 and HXT4[1][2][3][4]




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Interactions

Regulatory

SNF3 expression is repressed by high levels of glucose, via the Snf1-Mig1 glucose repression pathway. [5] [6]


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References

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  1. Ko CH, et al. (1993) Roles of multiple glucose transporters in Saccharomyces cerevisiae. Mol Cell Biol 13(1):638-48 SGD PMID 8417358
  2. Ozcan S, et al. (1996) Two glucose transporters in Saccharomyces cerevisiae are glucose sensors that generate a signal for induction of gene expression. Proc Natl Acad Sci U S A 93(22):12428-32 SGD PMID 8901598
  3. Ozcan S and Johnston M (1999) Function and regulation of yeast hexose transporters. Microbiol Mol Biol Rev 63(3):554-69 SGD PMID 10477308
  4. Vagnoli P, et al. (1998) The C-terminal domain of Snf3p mediates glucose-responsive signal transduction in Saccharomyces cerevisiae. FEMS Microbiol Lett 160(1):31-6 SGD PMID 9495009
  5. Ozcan S, et al. (1998) Glucose sensing and signaling by two glucose receptors in the yeast Saccharomyces cerevisiae. EMBO J 17(9):2566-73 SGD PMID 9564039
  6. submitted by Mark Johnston on 2003-03-11

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