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Systematic name YDL194W
Gene name SNF3
Feature type ORF, Verified
Coordinates Chr IV:111580..114234
Primary SGDID S000002353

Description of YDL194W: Plasma membrane low glucose sensor that regulates glucose transport; contains 12 predicted transmembrane segments and a long C-terminal tail required for induction of hexose transporters; also senses fructose and mannose; similar to Rgt2p[1][2][3][4][5]


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SNF3 expression is repressed by high levels of glucose, via the Snf1-Mig1 glucose repression pathway. [4] [6]



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  1. Dietvorst J, et al. (2010) Amino acid residues involved in ligand preference of the Snf3 transporter-like sensor in Saccharomyces cerevisiae. Yeast 27(3):131-8 SGD PMID 20014043
  2. Ko CH, et al. (1993) Roles of multiple glucose transporters in Saccharomyces cerevisiae. Mol Cell Biol 13(1):638-48 SGD PMID 8417358
  3. Ozcan S, et al. (1996) Two glucose transporters in Saccharomyces cerevisiae are glucose sensors that generate a signal for induction of gene expression. Proc Natl Acad Sci U S A 93(22):12428-32 SGD PMID 8901598
  4. 4.0 4.1 Ozcan S, et al. (1998) Glucose sensing and signaling by two glucose receptors in the yeast Saccharomyces cerevisiae. EMBO J 17(9):2566-73 SGD PMID 9564039
  5. Vagnoli P, et al. (1998) The C-terminal domain of Snf3p mediates glucose-responsive signal transduction in Saccharomyces cerevisiae. FEMS Microbiol Lett 160(1):31-6 SGD PMID 9495009
  6. submitted by Mark Johnston on 2003-03-11

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