Difference between revisions of "YDL133W"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000002291 YDL133W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''SRF1 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''SRF1 '' | ||
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| − | '''Description of YDL133W:''' Regulator of phospholipase D (Spo14p); interacts with Spo14p and regulates its catalytic activity; capable of buffering the toxicity of C16:0 platelet activating factor, a lipid that | + | '''Description of YDL133W:''' Regulator of phospholipase D (Spo14p); interacts with Spo14p and regulates its catalytic activity; capable of buffering the toxicity of C16:0 platelet activating factor, a lipid that accumulates intraneuronally in Alzheimer's patients<ref name='S000119159'>Fisk DG, et al. (2006) Saccharomyces cerevisiae S288C genome annotation: a working hypothesis. Yeast 23(12):857-65 {{SGDpaper|S000119159}} PMID 17001629</ref><ref name='S000144461'>Kennedy MA, et al. (2011) Srf1 is a novel regulator of phospholipase d activity and is essential to buffer the toxic effects of c16:0 platelet activating factor. PLoS Genet 7(2):e1001299 |
{{SGDpaper|S000144461}} PMID 21347278</ref> | {{SGDpaper|S000144461}} PMID 21347278</ref> | ||
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Latest revision as of 07:45, 23 January 2012
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| Systematic name | YDL133W |
| Gene name | SRF1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr IV:222427..223740 |
| Primary SGDID | S000002291 |
Description of YDL133W: Regulator of phospholipase D (Spo14p); interacts with Spo14p and regulates its catalytic activity; capable of buffering the toxicity of C16:0 platelet activating factor, a lipid that accumulates intraneuronally in Alzheimer's patients[1][2]
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References
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- ↑ Fisk DG, et al. (2006) Saccharomyces cerevisiae S288C genome annotation: a working hypothesis. Yeast 23(12):857-65 SGD PMID 17001629
- ↑ Kennedy MA, et al. (2011) Srf1 is a novel regulator of phospholipase d activity and is essential to buffer the toxic effects of c16:0 platelet activating factor. PLoS Genet 7(2):e1001299 SGD PMID 21347278
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