YDL126C

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Systematic name YDL126C
Gene name CDC48
Aliases
Feature type ORF, Verified
Coordinates Chr IV:238664..236157
Primary SGDID S000002284


Description of YDL126C: ATPase involved in ubiquitin-mediated protein degradation; Cdc48p-Npl4p-Ufd1p complex participates in ER-associated degradation (ERAD) while Cdc48p-Npl4p-Vms1p complex participates in mitochondria-associated degradation (MAD)[1][2]




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References

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  1. Heo JM, et al. (2010) A stress-responsive system for mitochondrial protein degradation. Mol Cell 40(3):465-80 SGD PMID 21070972
  2. Ye Y, et al. (2003) Function of the p97-Ufd1-Npl4 complex in retrotranslocation from the ER to the cytosol: dual recognition of nonubiquitinated polypeptide segments and polyubiquitin chains. J Cell Biol 162(1):71-84 SGD PMID 12847084

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