YDL002C

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Systematic name YDL002C
Gene name NHP10
Aliases HMO2
Feature type ORF, Verified
Coordinates Chr IV:447576..446965
Primary SGDID S000002160


Description of YDL002C: Protein related to mammalian high mobility group proteins; binds preferentially to DNA ends and is able to protect them from exonuclease cleavage; likely component of the INO80 complex, which is an ATP-dependent chromatin-remodeling complex[1][2][3]




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References

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  1. Lu J, et al. (1996) Characterization of a high mobility group 1/2 homolog in yeast. J Biol Chem 271(52):33678-85 SGD PMID 8969238
  2. Shen X, et al. (2003) Involvement of actin-related proteins in ATP-dependent chromatin remodeling. Mol Cell 12(1):147-55 SGD PMID 12887900
  3. Ray S and Grove A (2009) The yeast high mobility group protein HMO2, a subunit of the chromatin-remodeling complex INO80, binds DNA ends. Nucleic Acids Res 37(19):6389-99 SGD PMID 19726587

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