YDL002C

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Systematic name YDL002C
Gene name NHP10
Aliases HMO2
Feature type ORF, Verified
Coordinates Chr IV:447578..446967
Primary SGDID S000002160


Description of YDL002C: Protein related to mammalian high mobility group proteins; preferentially binds DNA ends, protecting them from exonucleatic cleavage; likely component of the chromatin-remodeling complex INO80 complex; proposed to be involved in DNA repair[1][2][3][4][5]




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References

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  1. Conaway RC and Conaway JW (2009) The INO80 chromatin remodeling complex in transcription, replication and repair. Trends Biochem Sci 34(2):71-7 SGD PMID 19062292
  2. Lu J, et al. (1996) Characterization of a high mobility group 1/2 homolog in yeast. J Biol Chem 271(52):33678-85 SGD PMID 8969238
  3. Morrison AJ, et al. (2004) INO80 and gamma-H2AX interaction links ATP-dependent chromatin remodeling to DNA damage repair. Cell 119(6):767-75 SGD PMID 15607974
  4. Ray S and Grove A (2009) The yeast high mobility group protein HMO2, a subunit of the chromatin-remodeling complex INO80, binds DNA ends. Nucleic Acids Res 37(19):6389-99 SGD PMID 19726587
  5. Shen X, et al. (2003) Involvement of actin-related proteins in ATP-dependent chromatin remodeling. Mol Cell 12(1):147-55 SGD PMID 12887900

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