Difference between revisions of "YCR088W"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000000684 YCR088W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''ABP1 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''ABP1 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr III: | + | |nowrap| Chr III:265068..266846 |
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| + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000000684 | ||
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| − | '''Description of | + | '''Description of YCR088W:''' Actin-binding protein of the cortical actin cytoskeleton, important for activation of the Arp2/3 complex that plays a key role actin in cytoskeleton organization; phosphorylation within its PRR (Proline-Rich Region), mediated by Cdc28p and Pho85p, protects Abp1p from proteolysis mediated by its own PEST sequences<ref name='S000043720'>Drubin DG, et al. (1990) Homology of a yeast actin-binding protein to signal transduction proteins and myosin-I. Nature 343(6255):288-90 {{SGDpaper|S000043720}} PMID 2405279</ref><ref name='S000149711'>Garcia B, et al. (2012) The Importance of Conserved Features of Yeast Actin Binding Protein 1 (Abp1p): the Conditional Nature of Essentiality. Genetics () {{SGDpaper|S000149711}} PMID 22661326</ref><ref name='S000042854'>Mulholland J, et al. (1994) Ultrastructure of the yeast actin cytoskeleton and its association with the plasma membrane. J Cell Biol 125(2):381-91 {{SGDpaper|S000042854}} PMID 8163554</ref><ref name='S000074351'>Olazabal IM and Machesky LM (2001) Abp1p and cortactin, new hand-holds for actin. J Cell Biol 154(4):679-82 |
| − | {{SGDpaper| | + | {{SGDpaper|S000074351}} PMID 11514584</ref> |
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==Community Commentary== | ==Community Commentary== | ||
{{CommentaryHelp}} | {{CommentaryHelp}} | ||
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| + | <!-- PLEASE ADD Community Commentary ABOVE THIS MESSAGE. See below for an example of community annotation --> | ||
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| + | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
| + | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
| + | J Biol Chem 278(5):3265-74</ref> | ||
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Latest revision as of 14:05, 22 June 2012
Share your knowledge...Edit this entry! <protect>
| Systematic name | YCR088W |
| Gene name | ABP1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr III:265068..266846 |
| Primary SGDID | S000000684 |
Description of YCR088W: Actin-binding protein of the cortical actin cytoskeleton, important for activation of the Arp2/3 complex that plays a key role actin in cytoskeleton organization; phosphorylation within its PRR (Proline-Rich Region), mediated by Cdc28p and Pho85p, protects Abp1p from proteolysis mediated by its own PEST sequences[1][2][3][4]
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Community Commentary
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References
See Help:References on how to add references
- ↑ Drubin DG, et al. (1990) Homology of a yeast actin-binding protein to signal transduction proteins and myosin-I. Nature 343(6255):288-90 SGD PMID 2405279
- ↑ Garcia B, et al. (2012) The Importance of Conserved Features of Yeast Actin Binding Protein 1 (Abp1p): the Conditional Nature of Essentiality. Genetics () SGD PMID 22661326
- ↑ Mulholland J, et al. (1994) Ultrastructure of the yeast actin cytoskeleton and its association with the plasma membrane. J Cell Biol 125(2):381-91 SGD PMID 8163554
- ↑ Olazabal IM and Machesky LM (2001) Abp1p and cortactin, new hand-holds for actin. J Cell Biol 154(4):679-82 SGD PMID 11514584
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