Difference between revisions of "YCR088W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000000684 YCR088W]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000000684 YCR088W]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''ABP1 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''ABP1 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr III:265065..266843
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|nowrap| Chr III:265068..266846
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000000684
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000000684
 
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'''Description of YCR088W:''' Actin-binding protein of the cortical actin cytoskeleton, important for activation of the Arp2/3 complex that plays a key role actin in cytoskeleton organization<ref name='S000043720'>Drubin DG, et al. (1990) Homology of a yeast actin-binding protein to signal transduction proteins and myosin-I. Nature 343(6255):288-90 {{SGDpaper|S000043720}} PMID 2405279</ref><ref name='S000042854'>Mulholland J, et al. (1994) Ultrastructure of the yeast actin cytoskeleton and its association with the plasma membrane. J Cell Biol 125(2):381-91 {{SGDpaper|S000042854}} PMID 8163554</ref><ref name='S000074351'>Olazabal IM and Machesky LM (2001) Abp1p and cortactin, new hand-holds for actin. J Cell Biol 154(4):679-82
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'''Description of YCR088W:''' Actin-binding protein of the cortical actin cytoskeleton, important for activation of the Arp2/3 complex that plays a key role actin in cytoskeleton organization; phosphorylation within its PRR (Proline-Rich Region), mediated by Cdc28p and Pho85p, protects Abp1p from proteolysis mediated by its own PEST sequences<ref name='S000043720'>Drubin DG, et al. (1990) Homology of a yeast actin-binding protein to signal transduction proteins and myosin-I. Nature 343(6255):288-90 {{SGDpaper|S000043720}} PMID 2405279</ref><ref name='S000149711'>Garcia B, et al. (2012) The Importance of Conserved Features of Yeast Actin Binding Protein 1 (Abp1p): the Conditional Nature of Essentiality. Genetics () {{SGDpaper|S000149711}} PMID 22661326</ref><ref name='S000042854'>Mulholland J, et al. (1994) Ultrastructure of the yeast actin cytoskeleton and its association with the plasma membrane. J Cell Biol 125(2):381-91 {{SGDpaper|S000042854}} PMID 8163554</ref><ref name='S000074351'>Olazabal IM and Machesky LM (2001) Abp1p and cortactin, new hand-holds for actin. J Cell Biol 154(4):679-82
 
  {{SGDpaper|S000074351}} PMID 11514584</ref>
 
  {{SGDpaper|S000074351}} PMID 11514584</ref>
 
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Latest revision as of 14:05, 22 June 2012

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Systematic name YCR088W
Gene name ABP1
Aliases
Feature type ORF, Verified
Coordinates Chr III:265068..266846
Primary SGDID S000000684


Description of YCR088W: Actin-binding protein of the cortical actin cytoskeleton, important for activation of the Arp2/3 complex that plays a key role actin in cytoskeleton organization; phosphorylation within its PRR (Proline-Rich Region), mediated by Cdc28p and Pho85p, protects Abp1p from proteolysis mediated by its own PEST sequences[1][2][3][4]




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References

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  1. Drubin DG, et al. (1990) Homology of a yeast actin-binding protein to signal transduction proteins and myosin-I. Nature 343(6255):288-90 SGD PMID 2405279
  2. Garcia B, et al. (2012) The Importance of Conserved Features of Yeast Actin Binding Protein 1 (Abp1p): the Conditional Nature of Essentiality. Genetics () SGD PMID 22661326
  3. Mulholland J, et al. (1994) Ultrastructure of the yeast actin cytoskeleton and its association with the plasma membrane. J Cell Biol 125(2):381-91 SGD PMID 8163554
  4. Olazabal IM and Machesky LM (2001) Abp1p and cortactin, new hand-holds for actin. J Cell Biol 154(4):679-82 SGD PMID 11514584

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