Difference between revisions of "YCL033C"

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'''Description of YCL033C:''' Putative protein-methionine-R-oxide reductase; involved in response to oxidative stress; similar to mouse Sepx1p, fly SelRp, and E. coli MsrB<ref name='S000128503'>Le DT, et al. (2009) Functional Analysis of Free Methionine-R-sulfoxide Reductase from Saccharomyces cerevisiae. J Biol Chem 284(7):4354-64 {{SGDpaper|S000128503}} PMID 19049972</ref><ref name='S000069481'>Kryukov GV, et al. (2002) Selenoprotein R is a zinc-containing stereo-specific methionine sulfoxide reductase. Proc Natl Acad Sci U S A 99(7):4245-50
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'''Description of YCL033C:''' Methionine-R-sulfoxide reductase, involved in the response to oxidative stress; protects iron-sulfur clusters from oxidative inactivation along with MXR1; involved in the regulation of lifespan<ref name='S000129314'>Sideri TC, et al. (2009) Methionine sulphoxide reductases protect iron-sulphur clusters from oxidative inactivation in yeast. Microbiology 155(Pt 2):612-23 {{SGDpaper|S000129314}} PMID 19202110</ref><ref name='S000128503'>Le DT, et al. (2009) Functional Analysis of Free Methionine-R-sulfoxide Reductase from Saccharomyces cerevisiae. J Biol Chem 284(7):4354-64 {{SGDpaper|S000128503}} PMID 19049972</ref><ref name='S000076628'>Koc A, et al. (2004) Methionine sulfoxide reductase regulation of yeast lifespan reveals reactive oxygen species-dependent and -independent components of aging. Proc Natl Acad Sci U S A 101(21):7999-8004 {{SGDpaper|S000076628}} PMID 15141092</ref><ref name='S000069481'>Kryukov GV, et al. (2002) Selenoprotein R is a zinc-containing stereo-specific methionine sulfoxide reductase. Proc Natl Acad Sci U S A 99(7):4245-50
 
  {{SGDpaper|S000069481}} PMID 11929995</ref>
 
  {{SGDpaper|S000069481}} PMID 11929995</ref>
 
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Revision as of 14:05, 25 February 2009

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Systematic name YCL033C
Gene name MXR2
Aliases MSRB
Feature type ORF, Verified
Coordinates Chr III:63282..62776
Primary SGDID S000000538


Description of YCL033C: Methionine-R-sulfoxide reductase, involved in the response to oxidative stress; protects iron-sulfur clusters from oxidative inactivation along with MXR1; involved in the regulation of lifespan[1][2][3][4]




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References

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  1. Sideri TC, et al. (2009) Methionine sulphoxide reductases protect iron-sulphur clusters from oxidative inactivation in yeast. Microbiology 155(Pt 2):612-23 SGD PMID 19202110
  2. Le DT, et al. (2009) Functional Analysis of Free Methionine-R-sulfoxide Reductase from Saccharomyces cerevisiae. J Biol Chem 284(7):4354-64 SGD PMID 19049972
  3. Koc A, et al. (2004) Methionine sulfoxide reductase regulation of yeast lifespan reveals reactive oxygen species-dependent and -independent components of aging. Proc Natl Acad Sci U S A 101(21):7999-8004 SGD PMID 15141092
  4. Kryukov GV, et al. (2002) Selenoprotein R is a zinc-containing stereo-specific methionine sulfoxide reductase. Proc Natl Acad Sci U S A 99(7):4245-50 SGD PMID 11929995

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