YCL033C

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Systematic name YCL033C
Gene name MXR2
Aliases MSRB
Feature type ORF, Verified
Coordinates Chr III:63282..62776
Primary SGDID S000000538


Description of YCL033C: Methionine-R-sulfoxide reductase, involved in the response to oxidative stress; protects iron-sulfur clusters from oxidative inactivation along with MXR1; involved in the regulation of lifespan[1][2][3][4]




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References

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  1. Koc A, et al. (2004) Methionine sulfoxide reductase regulation of yeast lifespan reveals reactive oxygen species-dependent and -independent components of aging. Proc Natl Acad Sci U S A 101(21):7999-8004 SGD PMID 15141092
  2. Kryukov GV, et al. (2002) Selenoprotein R is a zinc-containing stereo-specific methionine sulfoxide reductase. Proc Natl Acad Sci U S A 99(7):4245-50 SGD PMID 11929995
  3. Le DT, et al. (2009) Functional Analysis of Free Methionine-R-sulfoxide Reductase from Saccharomyces cerevisiae. J Biol Chem 284(7):4354-64 SGD PMID 19049972
  4. Sideri TC, et al. (2009) Methionine sulphoxide reductases protect iron-sulphur clusters from oxidative inactivation in yeast. Microbiology 155(Pt 2):612-23 SGD PMID 19202110

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