Difference between revisions of "YCL016C"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl? | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000000521 YCL016C] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''DCC1 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''DCC1 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
|nowrap| Chr III:95763..94621 | |nowrap| Chr III:95763..94621 | ||
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| + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000000521 | ||
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| − | '''Description of | + | '''Description of YCL016C:''' Subunit of a complex with Ctf8p and Ctf18p that shares some components with Replication Factor C, required for sister chromatid cohesion and telomere length maintenance<ref name='S000114270'>Askree SH, et al. (2004) A genome-wide screen for Saccharomyces cerevisiae deletion mutants that affect telomere length. Proc Natl Acad Sci U S A 101(23):8658-63 {{SGDpaper|S000114270}} PMID 15161972</ref><ref name='S000060777'>Mayer ML, et al. (2001) Identification of RFC(Ctf18p, Ctf8p, Dcc1p): an alternative RFC complex required for sister chromatid cohesion in S. cerevisiae. Mol Cell 7(5):959-70 |
{{SGDpaper|S000060777}} PMID 11389843</ref> | {{SGDpaper|S000060777}} PMID 11389843</ref> | ||
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J Biol Chem 278(5):3265-74</ref> | J Biol Chem 278(5):3265-74</ref> | ||
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Revision as of 08:45, 27 February 2007
Share your knowledge...Edit this entry! <protect>
| Systematic name | YCL016C |
| Gene name | DCC1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr III:95763..94621 |
| Primary SGDID | S000000521 |
Description of YCL016C: Subunit of a complex with Ctf8p and Ctf18p that shares some components with Replication Factor C, required for sister chromatid cohesion and telomere length maintenance[1][2]
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Contents
Community Commentary
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Alleles, Strains, and Phenotypes
Complete Deletion
Phenotype(s): Viable
Deletion mutant is defective in telomere positioning to nuclear periphery. [3] [4]
Multiple Knockout Strains
Together with: RAD9, CTF8
Phenotype(s): Viable
dcc1 rad9 double deletion strain is defective in phosphorylation of Rad53p and shows higher sensitivity to HU and MMS than WT and single mutant strains. [5] [4]
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References
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- ↑ Askree SH, et al. (2004) A genome-wide screen for Saccharomyces cerevisiae deletion mutants that affect telomere length. Proc Natl Acad Sci U S A 101(23):8658-63 SGD PMID 15161972
- ↑ Mayer ML, et al. (2001) Identification of RFC(Ctf18p, Ctf8p, Dcc1p): an alternative RFC complex required for sister chromatid cohesion in S. cerevisiae. Mol Cell 7(5):959-70 SGD PMID 11389843
- ↑ Hiraga S, et al. (2006) The Ctf18 RFC-like complex positions yeast telomeres but does not specify their replication time. EMBO J 25(7):1505-14 SGD PMID 16525505
- ↑ 4.0 4.1 submitted by Shin-ichiro Hiraga on 2006-06-20
- ↑ Pan X, et al. (2006) A DNA integrity network in the yeast Saccharomyces cerevisiae. Cell 124(5):1069-81 SGD PMID 16487579
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