YCL016C
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| Systematic name | YCL016C |
| Gene name | DCC1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr III:95763..94621 |
| Primary SGDID | S000000521 |
Description of YCL016C: Subunit of a complex with Ctf8p and Ctf18p that shares some components with Replication Factor C, required for sister chromatid cohesion and telomere length maintenance[1][2]
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Contents
Community Commentary
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Alleles, Strains, and Phenotypes
Complete Deletion
Phenotype(s): Viable
Deletion mutant is defective in telomere positioning to nuclear periphery. [3] [4]
Multiple Knockout Strains
Together with: RAD9, CTF8
Phenotype(s): Viable
dcc1 rad9 double deletion strain is defective in phosphorylation of Rad53p and shows higher sensitivity to HU and MMS than WT and single mutant strains. [5] [4]
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References
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- ↑ Askree SH, et al. (2004) A genome-wide screen for Saccharomyces cerevisiae deletion mutants that affect telomere length. Proc Natl Acad Sci U S A 101(23):8658-63 SGD PMID 15161972
- ↑ Mayer ML, et al. (2001) Identification of RFC(Ctf18p, Ctf8p, Dcc1p): an alternative RFC complex required for sister chromatid cohesion in S. cerevisiae. Mol Cell 7(5):959-70 SGD PMID 11389843
- ↑ Hiraga S, et al. (2006) The Ctf18 RFC-like complex positions yeast telomeres but does not specify their replication time. EMBO J 25(7):1505-14 SGD PMID 16525505
- ↑ 4.0 4.1 submitted by Shin-ichiro Hiraga on 2006-06-20
- ↑ Pan X, et al. (2006) A DNA integrity network in the yeast Saccharomyces cerevisiae. Cell 124(5):1069-81 SGD PMID 16487579
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