Difference between revisions of "YCL016C"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YCL016C YCL016C]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000000521 YCL016C]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''DCC1 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''DCC1 ''
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|nowrap| Chr III:95763..94621
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000000521
 
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'''Description of {{PAGENAME}}:''' Subunit of a complex with Ctf8p and Ctf18p that shares some components with Replication Factor C, required for sister chromatid cohesion and telomere length maintenance<ref name='S000114270'>Askree SH, et al. (2004) A genome-wide screen for Saccharomyces cerevisiae deletion mutants that affect telomere length. Proc Natl Acad Sci U S A 101(23):8658-63 {{SGDpaper|S000114270}} PMID 15161972</ref><ref name='S000060777'>Mayer ML, et al. (2001) Identification of RFC(Ctf18p, Ctf8p, Dcc1p): an alternative RFC complex required for sister chromatid cohesion in S. cerevisiae. Mol Cell 7(5):959-70
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'''Description of YCL016C:''' Subunit of a complex with Ctf8p and Ctf18p that shares some components with Replication Factor C, required for sister chromatid cohesion and telomere length maintenance<ref name='S000114270'>Askree SH, et al. (2004) A genome-wide screen for Saccharomyces cerevisiae deletion mutants that affect telomere length. Proc Natl Acad Sci U S A 101(23):8658-63 {{SGDpaper|S000114270}} PMID 15161972</ref><ref name='S000060777'>Mayer ML, et al. (2001) Identification of RFC(Ctf18p, Ctf8p, Dcc1p): an alternative RFC complex required for sister chromatid cohesion in S. cerevisiae. Mol Cell 7(5):959-70
 
  {{SGDpaper|S000060777}} PMID 11389843</ref>
 
  {{SGDpaper|S000060777}} PMID 11389843</ref>
 
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==Community Commentary==
 
==Community Commentary==
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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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==References==
 
==References==
 
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Latest revision as of 07:45, 23 January 2012

Share your knowledge...Edit this entry! <protect>

Systematic name YCL016C
Gene name DCC1
Aliases
Feature type ORF, Verified
Coordinates Chr III:95763..94621
Primary SGDID S000000521


Description of YCL016C: Subunit of a complex with Ctf8p and Ctf18p that shares some components with Replication Factor C, required for sister chromatid cohesion and telomere length maintenance[1][2]




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Community Commentary

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Alleles, Strains, and Phenotypes

Complete Deletion

Phenotype(s): Viable

Deletion mutant is defective in telomere positioning to nuclear periphery. [3] [4]


Multiple Knockout Strains

Together with: RAD9, CTF8
Phenotype(s): Viable

dcc1 rad9 double deletion strain is defective in phosphorylation of Rad53p and shows higher sensitivity to HU and MMS than WT and single mutant strains. [5] [4]





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References

See Help:References on how to add references

  1. Askree SH, et al. (2004) A genome-wide screen for Saccharomyces cerevisiae deletion mutants that affect telomere length. Proc Natl Acad Sci U S A 101(23):8658-63 SGD PMID 15161972
  2. Mayer ML, et al. (2001) Identification of RFC(Ctf18p, Ctf8p, Dcc1p): an alternative RFC complex required for sister chromatid cohesion in S. cerevisiae. Mol Cell 7(5):959-70 SGD PMID 11389843
  3. Hiraga S, et al. (2006) The Ctf18 RFC-like complex positions yeast telomeres but does not specify their replication time. EMBO J 25(7):1505-14 SGD PMID 16525505
  4. 4.0 4.1 submitted by Shin-ichiro Hiraga on 2006-06-20
  5. Pan X, et al. (2006) A DNA integrity network in the yeast Saccharomyces cerevisiae. Cell 124(5):1069-81 SGD PMID 16487579

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