Difference between revisions of "YBR212W"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000000416 YBR212W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''NGR1 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''NGR1 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr II: | + | |nowrap| Chr II:647886..649904 |
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| − | | | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000000416 |
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| − | '''Description of | + | '''Description of YBR212W:''' RNA binding protein that negatively regulates growth rate; interacts with the 3' UTR of the mitochondrial porin (POR1) mRNA and enhances its degradation; overexpression impairs mitochondrial function; interacts with Dhh1p to mediate POR1 mRNA decay; expressed in stationary phase<ref name='S000040994'>Akada R, et al. (1997) Screening and identification of yeast sequences that cause growth inhibition when overexpressed. Mol Gen Genet 254(3):267-74 {{SGDpaper|S000040994}} PMID 9150260</ref><ref name='S000075288'>Buu LM, et al. (2004) The yeast RNA-binding protein Rbp1p modifies the stability of mitochondrial porin mRNA. J Biol Chem 279(1):453-62 {{SGDpaper|S000075288}} PMID 14570877</ref><ref name='S000147179'>Chang LC and Lee FJ (2011) The RNA helicase Dhh1p cooperates with Rbp1p to promote porin mRNA decay via its non-conserved C-terminal domain. Nucleic Acids Res () {{SGDpaper|S000147179}} PMID 21998293</ref><ref name='S000057697'>Lee FJ and Moss J (1993) An RNA-binding protein gene (RBP1) of Saccharomyces cerevisiae encodes a putative glucose-repressible protein containing two RNA recognition motifs. J Biol Chem 268(20):15080-7 {{SGDpaper|S000057697}} PMID 8325883</ref><ref name='S000079745'>Martinez MJ, et al. (2004) Genomic analysis of stationary-phase and exit in Saccharomyces cerevisiae: gene expression and identification of novel essential genes. Mol Biol Cell 15(12):5295-305 |
| − | {{SGDpaper| | + | {{SGDpaper|S000079745}} PMID 15456898</ref> |
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==Community Commentary== | ==Community Commentary== | ||
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| + | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
| + | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
| + | J Biol Chem 278(5):3265-74</ref> | ||
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==References== | ==References== | ||
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Latest revision as of 07:45, 23 January 2012
Share your knowledge...Edit this entry! <protect>
| Systematic name | YBR212W |
| Gene name | NGR1 |
| Aliases | RBP1 |
| Feature type | ORF, Verified |
| Coordinates | Chr II:647886..649904 |
| Primary SGDID | S000000416 |
Description of YBR212W: RNA binding protein that negatively regulates growth rate; interacts with the 3' UTR of the mitochondrial porin (POR1) mRNA and enhances its degradation; overexpression impairs mitochondrial function; interacts with Dhh1p to mediate POR1 mRNA decay; expressed in stationary phase[1][2][3][4][5]
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References
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- ↑ Akada R, et al. (1997) Screening and identification of yeast sequences that cause growth inhibition when overexpressed. Mol Gen Genet 254(3):267-74 SGD PMID 9150260
- ↑ Buu LM, et al. (2004) The yeast RNA-binding protein Rbp1p modifies the stability of mitochondrial porin mRNA. J Biol Chem 279(1):453-62 SGD PMID 14570877
- ↑ Chang LC and Lee FJ (2011) The RNA helicase Dhh1p cooperates with Rbp1p to promote porin mRNA decay via its non-conserved C-terminal domain. Nucleic Acids Res () SGD PMID 21998293
- ↑ Lee FJ and Moss J (1993) An RNA-binding protein gene (RBP1) of Saccharomyces cerevisiae encodes a putative glucose-repressible protein containing two RNA recognition motifs. J Biol Chem 268(20):15080-7 SGD PMID 8325883
- ↑ Martinez MJ, et al. (2004) Genomic analysis of stationary-phase and exit in Saccharomyces cerevisiae: gene expression and identification of novel essential genes. Mol Biol Cell 15(12):5295-305 SGD PMID 15456898
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