YBR212W

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Systematic name YBR212W
Gene name NGR1
Aliases RBP1
Feature type ORF, Verified
Coordinates Chr II:647886..649904
Primary SGDID S000000416


Description of YBR212W: RNA binding protein that negatively regulates growth rate; interacts with the 3' UTR of the mitochondrial porin (POR1) mRNA and enhances its degradation; overexpression impairs mitochondrial function; interacts with Dhh1p to mediate POR1 mRNA decay; expressed in stationary phase[1][2][3][4][5]




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References

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  1. Akada R, et al. (1997) Screening and identification of yeast sequences that cause growth inhibition when overexpressed. Mol Gen Genet 254(3):267-74 SGD PMID 9150260
  2. Buu LM, et al. (2004) The yeast RNA-binding protein Rbp1p modifies the stability of mitochondrial porin mRNA. J Biol Chem 279(1):453-62 SGD PMID 14570877
  3. Chang LC and Lee FJ (2011) The RNA helicase Dhh1p cooperates with Rbp1p to promote porin mRNA decay via its non-conserved C-terminal domain. Nucleic Acids Res () SGD PMID 21998293
  4. Lee FJ and Moss J (1993) An RNA-binding protein gene (RBP1) of Saccharomyces cerevisiae encodes a putative glucose-repressible protein containing two RNA recognition motifs. J Biol Chem 268(20):15080-7 SGD PMID 8325883
  5. Martinez MJ, et al. (2004) Genomic analysis of stationary-phase and exit in Saccharomyces cerevisiae: gene expression and identification of novel essential genes. Mol Biol Cell 15(12):5295-305 SGD PMID 15456898

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